Map2k2

Gene Symbol	Map2k2
Entrez Gene	26396
Alt Symbol	AA589381, MEK2, MK2, Prkmk2
Species	Mouse
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase 2
Other Description	ERK activator kinase 2|MAP kinase kinase 2|MAP kinase/Erk kinase|MAPK/ERK kinase 2|MAPKK 2|MEK 2|dual specificity mitogen-activated protein kinase kinase 2|mitogen activated protein kinase kinase 2|protein kinase, mitogen activated, kinase 2, p45
Swissprots	Q9D7B0 Q63932
Accessions	EDL31456 EDL31457 EDL31458 EDL31459 EDL31460 Q63932 AK009392 BAB26261 AK011247 AK036822 BAC29592 AK080574 BAC37945 AK138130 AK140101 BAE24237 AK143425 BAE25372 AK171584 BAE42542 AK172055 BAE42803 AK176974 AK181352 AK181608 AK186012 AK186466 AK188207 AK189608 AK192399 AK194767 AK196030 AK197970 AK198385 AK202988 AK203048 AK203356 AK208021 AK209603 AK210224 AK212183 AK212483 AK212487 AK214840 AK216389 AK217783 AK219722 AK220136 BC014830 AAH14830 BE955857 S68267 AAC60678 XM_006513682 XP_006513745 XM_006513683 XP_006513746 XM_006513684 XP_006513747 NM_023138 NP_075627
Function	Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases. {ECO:0000269|PubMed:19219045}.
Tissue Specificity	Expressed in adult intestine, kidney, liver, lung, pancreas, spleen, thymus, and at high levels in the neonatal brain. Lower expression is found in adult brain and heart.
Top Pathways	Gap junction, Bladder cancer, Chronic myeloid leukemia, Melanoma, Long-term depression

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

SignalSilence ® MEK2 siRNA I (Mouse Specific) - 6402 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

SignalSilence ® MEK2 siRNA II (Mouse Specific) - 6403 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Mouse

MEK-2 CRISPR/Cas9 KO Plasmid (m) - sc-424032 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Mouse

MEK-2 HDR Plasmid (m) - sc-424032-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

MEK-2 Double Nickase Plasmid (m) - sc-424032-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

MEK-2 Double Nickase Plasmid (m2) - sc-424032-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

MEK-2 CRISPR Activation Plasmid (m) - sc-424032-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Mouse

MEK-2 CRISPR Activation Plasmid (m2) - sc-424032-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Mouse

MEK-2 Lentiviral Activation Particles (m) - sc-424032-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

MEK-2 Lentiviral Activation Particles (m2) - sc-424032-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

MEK-2 siRNA (m) - sc-35906 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Mouse

MEK-2 shRNA Plasmid (m) - sc-35906-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Mouse

MEK-2 shRNA (m) Lentiviral Particles - sc-35906-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Mouse

MISSION® esiRNA - EMU011371 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN35225 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND35225 from Sigma-Aldrich Category ZFN Kit

MAP2K2 siRNA (Mouse) - CRM4713 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Mouse

shRNA set against Mouse MAP2K2 (NM_023138.4) - SHH337543 from Creative biogene Category siRNA Species Reactivities Mouse

shRNA set against Mouse Map2k2(NM_023138.4) - SHH173423 from Creative biogene Category siRNA Species Reactivities Mouse

Mouse MAP2K2 siRNA - orb284189 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Mouse

MAP2K2 shRNA Plasmid (Mouse) - CHM4713 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Mouse

MAP2K2 miRNA 3'UTR clone - MiUTR1M-06908 from Creative biogene Species Reactivities Mouse

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