| Gene Symbol |
Klkb1
|
| Entrez Gene |
16621
|
| Alt Symbol |
APS, Kal-3, Kal3, Klk3, PSA
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
kallikrein B, plasma 1
|
| Other Description |
antigen, prostate specific|fletcher factor|kallikrein 3, plasma|kininogenin|plasma kallikrein|plasma prekallikrein
|
| Swissprots |
P26262 Q8R0P5
|
| Accessions |
EDL35544 P26262 BC026555 AAH26555 NM_008455 NP_032481
|
| Function |
The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
Complement and coagulation cascades
|