Gene Symbol | Klkb1 |
---|---|
Entrez Gene | 16621 |
Alt Symbol | APS, Kal-3, Kal3, Klk3, PSA |
Species | Mouse |
Gene Type | protein-coding |
Description | kallikrein B, plasma 1 |
Other Description | antigen, prostate specific|fletcher factor|kallikrein 3, plasma|kininogenin|plasma kallikrein|plasma prekallikrein |
Swissprots | P26262 Q8R0P5 |
Accessions | EDL35544 P26262 BC026555 AAH26555 NM_008455 NP_032481 |
Function | The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades |
plasma kallikrein CRISPR/Cas9 KO Plasmid (m) - sc-421307 from Santa Cruz Biotechnology
|
||||||||
plasma kallikrein HDR Plasmid (m) - sc-421307-HDR from Santa Cruz Biotechnology
|
||||||||
plasma kallikrein Double Nickase Plasmid (m) - sc-421307-NIC from Santa Cruz Biotechnology
|
||||||||
plasma kallikrein Double Nickase Plasmid (m2) - sc-421307-NIC-2 from Santa Cruz Biotechnology
|
||||||||
plasma kallikrein CRISPR Activation Plasmid (m) - sc-421307-ACT from Santa Cruz Biotechnology
|
||||||||
plasma kallikrein CRISPR Activation Plasmid (m2) - sc-421307-ACT-2 from Santa Cruz Biotechnology
|
||||||||
plasma kallikrein Lentiviral Activation Particles (m) - sc-421307-LAC from Santa Cruz Biotechnology
|
||||||||
plasma kallikrein Lentiviral Activation Particles (m2) - sc-421307-LAC-2 from Santa Cruz Biotechnology
|
||||||||
plasma kallikrein siRNA (m) - sc-40412 from Santa Cruz Biotechnology
|
||||||||
plasma kallikrein shRNA Plasmid (m) - sc-40412-SH from Santa Cruz Biotechnology
|
||||||||
plasma kallikrein shRNA (m) Lentiviral Particles - sc-40412-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN34408 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34408 from Sigma-Aldrich
|
||||||||
KLKB1 siRNA (Mouse) - CRM2238 from Cohesion Biosciences
|
||||||||
shRNA set against Mouse KLKB1 (NM_008455.2) - SHH326663 from Creative biogene
|
||||||||
KLKB1 shRNA Plasmid (Mouse) - CHM2238 from Cohesion Biosciences
|