CACNA2D1

Gene Symbol CACNA2D1
Entrez Gene 781
Alt Symbol CACNA2, CACNL2A, CCHL2A, LINC01112, lncRNA-N3
Species Human
Gene Type protein-coding
Description calcium channel, voltage-dependent, alpha 2/delta subunit 1
Other Description calcium channel, L type, alpha 2 polypeptide|dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit|voltage-dependent calcium channel subunit alpha-2/delta-1|voltage-gated calcium channel subunit alpha-2/delta-1
Swissprots Q9UD82 Q17R45 Q9UD80 Q9UD81 P54289
Accessions AAC78619 AAD20938 AAD51454 AAF03259 AAF19234 EAW76990 P54289 AI924415 AK055040 AK092048 AK299838 BAH13144 AL707206 AL833141 BC051339 BC117468 AAI17469 BC117470 AAI17471 BG055272 BI545104 BP258070 BU501177 M76559 AAA51903 XM_005250570 XP_005250627 XM_005250572 XP_005250629 XM_005250573 XP_005250630 XM_005250574 XP_005250631 XM_006716118 XP_006716181 XM_006716119 XP_006716182 XM_006716120 XP_006716183 XM_006716121 XP_006716184 XM_011516570 XP_011514872 XM_011516571 XP_011514873 XM_011516572 XP_011514874 XM_011516573 XP_011514875 XM_011516574 XP_011514876 NM_000722 NP_000713 NM_001302890 NP_001289819
Function The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Isoform 1 is expressed in skeletal muscle. Isoform 2 is expressed in the central nervous system. Isoform 2, isoform 4 and isoform 5 are expressed in neuroblastoma cells. Isoform 3, isoform 4 and isoform 5 are expressed in the aorta. {ECO:0000269|PubMed:1309651, ECO:0000269|PubMed:8107964}.
Top Pathways MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

Cacna2d1 CRISPR/Cas9 KO Plasmid (h) - sc-402833 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cacna2d1 HDR Plasmid (h) - sc-402833-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cacna2d1 Double Nickase Plasmid (h) - sc-402833-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cacna2d1 Double Nickase Plasmid (h2) - sc-402833-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cacna2d1 CRISPR Activation Plasmid (h) - sc-402833-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cacna2d1 CRISPR Activation Plasmid (h2) - sc-402833-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cacna2d1 Lentiviral Activation Particles (h) - sc-402833-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cacna2d1 Lentiviral Activation Particles (h2) - sc-402833-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cacna2d1 siRNA (h) - sc-89621 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cacna2d1 shRNA Plasmid (h) - sc-89621-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cacna2d1 shRNA (h) Lentiviral Particles - sc-89621-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU061081 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1789 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1789 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02688 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02688

CACNA2D1 siRNA (Human) - CRH0546 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CACNA2D1 RNAi - H00000781-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CACNA2D1 - MBS8221801 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CACNA2D1 (NM_000722.2) - SHH253369 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CACNA2D1(NM_000722.2) - SHG131569 from Creative biogene

Category siRNA
Species Reactivities Human

Human CACNA2D1 siRNA - orb261048 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CACNA2D1 shRNA Plasmid (Human) - CHH0546 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CACNA2D1 miRNA 3'UTR clone - MiUTR1H-01599 from Creative biogene

Species Reactivities Human
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