SLIT1

Gene Symbol SLIT1
Entrez Gene 6585
Alt Symbol MEGF4, SLIL1, SLIT-1, SLIT3
Species Human
Gene Type protein-coding
Description slit homolog 1 (Drosophila)
Other Description multiple EGF-like domains protein 4|multiple epidermal growth factor-like domains protein 4|slit homolog 1 protein
Swissprots Q9UIL7 Q8WWZ2 Q5T0V1 O75093
Accessions EAW49956 EAW49957 EAW49958 EAW49959 O75093 AB011537 BAA32465 AB017167 BAA35184 AY029183 AAK31796 BC028105 BC139909 BC146761 AAI46762 BC146851 AAI46852 CD671648 NM_003061 NP_003052
Function Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. {ECO:0000250}.
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney. {ECO:0000269|PubMed:9813312}.
Top Pathways Axon guidance

Slit1 CRISPR/Cas9 KO Plasmid (h) - sc-404033 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slit1 HDR Plasmid (h) - sc-404033-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slit1 Double Nickase Plasmid (h) - sc-404033-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slit1 Double Nickase Plasmid (h2) - sc-404033-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slit1 CRISPR Activation Plasmid (h) - sc-404033-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slit1 CRISPR Activation Plasmid (h2) - sc-404033-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slit1 Lentiviral Activation Particles (h) - sc-404033-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slit1 Lentiviral Activation Particles (h2) - sc-404033-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slit1 siRNA (h) - sc-42256 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Slit1 shRNA Plasmid (h) - sc-42256-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Slit1 shRNA (h) Lentiviral Particles - sc-42256-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Slit3 RNAi - H00006586-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN19726 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19726 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SLIT1 siRNA (Human) - CRH4473 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Slit1 RNAi - H00006585-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

SLIT1 - MBS828705 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLIT1 (NM_003061.2) - SHH412680 from Creative biogene

Category siRNA
Species Reactivities Human

SLIT1 shRNA Plasmid (Human) - CHH4473 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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