| Gene Symbol |
RHOF
|
| Entrez Gene |
54509
|
| Alt Symbol |
ARHF, RIF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ras homolog family member F (in filopodia)
|
| Other Description |
ras homolog gene family, member F (in filopodia)|rho family GTPase Rif|rho in filopodia|rho-related GTP-binding protein RhoF
|
| Swissprots |
Q9NXH6 Q8WVB1 Q9HBH0
|
| Accessions |
CAI61864 EAW98278 EAW98279 Q9HBH0 AF239923 AAG24952 AK000254 BAA91034 AK130459 AK289482 BAF82171 BC018208 AAH18208 BC018721 BC032529 BC043395 BG574506 BM830620 BQ053707 BQ422695 BU527972 CA426077 NM_019034 NP_061907
|
| Function |
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm, cytoskeleton.
|