OXCT1

Gene Symbol OXCT1
Entrez Gene 5019
Alt Symbol OXCT, SCOT
Species Human
Gene Type protein-coding
Description 3-oxoacid CoA transferase 1
Other Description 3-oxoacid CoA-transferase 1|3-oxoacid-CoA transferase 1|SCOT-s|somatic-type succinyl CoA:3-oxoacid CoA-transferase|somatic-type succinyl-CoA:3-oxoacid CoA-transferase|somatic-type succinyl-CoA:3-oxoacid-CoA-transferase|succinyl CoA:3-oxoacid CoA transferase|succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial|succinyl-CoA:3-ketoacid-CoA transferase|succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
Swissprots P55809 B7Z528 B2R5V2
Accessions BAB13733 BAC19838 CBX51364 EAW56014 EAW56015 P55809 AK125115 AK298352 BAH12764 AK299668 BAH13095 AK312327 BAG35249 AK315902 BAH14273 BC009001 AAH09001 BE244429 CR457049 CAG33330 DQ891805 ABM82731 DQ894989 ABM85915 EF095213 ABL01517 U62961 AAB07366 XR_427658 NM_000436 NP_000427
Function Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
Subcellular Location Mitochondrion matrix.
Tissue Specificity Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts.
Top Pathways Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism

SCOT (G-14) - sc-160776 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SCOT (G-14): sc-160776. Western blot analysis of SCOT expression in HeLa (A) and Jurkat (B) whole cell lysates and human heart tissue extract (C).

SCOT (A-23) - sc-133988 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
SCOT (A-23): sc-133988. Western blot analysis of SCOT expression in mouse heart tissue extract.

SCOT (H-54) - sc-382038 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-OXCT1 antibody - ab105320 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-OXCT1 antibody (ab105320) at 1/500 dilutionLane 1 : Human fetal heart lysateLane 2 : Human fetal brain lysate

Anti-OXCT1 antibody - ab70413 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-OXCT1 antibody (ab70413) at 1/500 dilutionLane 1 : OXCT1 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-OXCT1 Antibody (aa316-365) - LS-C81248 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-OXCT1 Antibody (aa140-189) - LS-C81247 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.

Anti-OXCT1 Antibody - LS-C317823 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial antibody at 2 ug/ml with HeLa whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 56 KDa. Observed band size: 56 KDa.

Anti-OXCT1 Antibody (FITC) - LS-C317820 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-OXCT1 Antibody (Biotin) - LS-C317817 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-OXCT1 Antibody (HRP) - LS-C317821 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

OXCT1 Antibody - NBP1-82462 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: OXCT1 Antibody [NBP1-82462] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

OXCT1 Antibody - H00005019-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: OXCT1 Antibody [H00005019-B01P] - Analysis of OXCT1 expression in transfected 293T cell line by OXCT1 polyclonal antibody. Lane 1: OXCT1 transfected lysate(57.2 KDa). Lane 2: Non-transfected lysate.

OXCT1 Antibody - 36880002 from Novus Biologicals

Prices $299.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

OXCT1 Antibody - H00005019-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: OXCT1 Antibody [H00005019-D01P] - Analysis of OXCT1 expression in Jurkat.

OXCT1 Antibody - H00005019-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-OXCT1 (AB1) antibody produced in rabbit - AV48480 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HeLa (<B>Cat. No. AV48480</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 0.5 μg/mL in cell type HeLa

Anti-OXCT1 antibody produced in rabbit - HPA012047 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-OXCT1: <B>Cat. No. HPA012047</B>: Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes.

Anti-OXCT1 antibody produced in mouse - SAB1406207 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-OXCT1: <B>Cat. No. SAB1406207</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-OXCT1 (291-305) antibody produced in rabbit - SAB1100355 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-OXCT1 (291-305), <B>Cat. No. SAB1100355</B>: Immunofluorescence of HUVEC cells using Anti-OXCT1 (291-305), SAB1100355 (red), taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-OXCT1 (AB2) antibody produced in rabbit - AV48481 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV48481</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type HepG2

Anti-OXCT1 (32-44) antibody produced in rabbit - SAB1100354 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-OXCT1 (32-44), <B>Cat. No. SAB1100354</B>: Immunofluorescence of HUVEC cells using Anti-OXCT1 (32-44), SAB1100354 (red), taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

OXCT1 antibody - N-terminal region (ARP48480_P050) - ARP48480_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OXCT1 antibody - middle region (ARP48481_P050) - ARP48481_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OXCT1 antibody - orb77768 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of fetal heart and brain lysate using OXCT1 antibody
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