OXCT1

Gene Symbol OXCT1
Entrez Gene 5019
Alt Symbol OXCT, SCOT
Species Human
Gene Type protein-coding
Description 3-oxoacid CoA transferase 1
Other Description 3-oxoacid CoA-transferase 1|3-oxoacid-CoA transferase 1|SCOT-s|somatic-type succinyl CoA:3-oxoacid CoA-transferase|somatic-type succinyl-CoA:3-oxoacid CoA-transferase|somatic-type succinyl-CoA:3-oxoacid-CoA-transferase|succinyl CoA:3-oxoacid CoA transferase|succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial|succinyl-CoA:3-ketoacid-CoA transferase|succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
Swissprots P55809 B7Z528 B2R5V2
Accessions BAB13733 BAC19838 CBX51364 EAW56014 EAW56015 P55809 AK125115 AK298352 BAH12764 AK299668 BAH13095 AK312327 BAG35249 AK315902 BAH14273 BC009001 AAH09001 BE244429 CR457049 CAG33330 DQ891805 ABM82731 DQ894989 ABM85915 EF095213 ABL01517 U62961 AAB07366 XR_427658 NM_000436 NP_000427
Function Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
Subcellular Location Mitochondrion matrix.
Tissue Specificity Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts.
Top Pathways Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism

SCOT CRISPR/Cas9 KO Plasmid (h) - sc-404705 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCOT HDR Plasmid (h) - sc-404705-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCOT Double Nickase Plasmid (h) - sc-404705-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCOT Double Nickase Plasmid (h2) - sc-404705-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCOT CRISPR Activation Plasmid (h) - sc-404705-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCOT CRISPR Activation Plasmid (h2) - sc-404705-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCOT Lentiviral Activation Particles (h) - sc-404705-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCOT Lentiviral Activation Particles (h2) - sc-404705-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCOT siRNA (h) - sc-91720 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SCOT shRNA Plasmid (h) - sc-91720-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SCOT shRNA (h) Lentiviral Particles - sc-91720-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OXCT1 RNAi - H00005019-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU007811 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16214 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16214 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

OXCT1 siRNA (Human) - CRH3333 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human OXCT1(NM_000436.3) - SHR084138 from Creative biogene

Category siRNA
Species Reactivities Human

Human OXCT1 siRNA - orb263835 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

OXCT1 shRNA Plasmid (Human) - CHH3333 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

OXCT1 miRNA 3'UTR clone - MiUTR1H-07425 from Creative biogene

Species Reactivities Human
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