ATP2A1

Gene Symbol ATP2A1
Entrez Gene 487
Alt Symbol ATP2A, SERCA1
Species Human
Gene Type protein-coding
Description ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Other Description SR Ca(2+)-ATPase 1|calcium pump 1|calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform|endoplasmic reticulum class 1/2 Ca(2+) ATPase|sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Swissprots O14983 A8K5J9 B3KY17 O14984
Accessions AAB53112 AAB53113 CBG22289 CBV35450 EAW52006 O14983 AK092691 BAG52597 AK128456 BAG54679 AK291314 BAF84003 AL706356 BC037354 AAH37354 BC104452 BC104453 BC148653 AAI48654 BU737186 BX537389 CAD97631 BX537784 CAD97841 BX647365 BX647366 BX647367 BX647368 BX648544 BX649072 EF139859 EF139860 NM_001286075 NP_001273004 NM_004320 NP_004311 NM_173201 NP_775293
Function Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity Skeletal muscle, fast twitch muscle (type II) fibers.
Top Pathways Alzheimer's disease, Calcium signaling pathway, Pancreatic secretion, cGMP-PKG signaling pathway

SERCA1 CRISPR/Cas9 KO Plasmid (h) - sc-401416 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERCA1 HDR Plasmid (h) - sc-401416-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERCA1 Double Nickase Plasmid (h) - sc-401416-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERCA1 Double Nickase Plasmid (h2) - sc-401416-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERCA1 CRISPR Activation Plasmid (h) - sc-401416-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERCA1 CRISPR Activation Plasmid (h2) - sc-401416-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERCA1 Lentiviral Activation Particles (h) - sc-401416-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERCA1 Lentiviral Activation Particles (h2) - sc-401416-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SERCA1 siRNA (h) - sc-36482 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SERCA1 shRNA Plasmid (h) - sc-36482-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SERCA1 shRNA (h) Lentiviral Particles - sc-36482-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SERCA1 ATPase RNAi - H00000487-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU064591 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2205 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2205 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02139 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02139

ATP2A1 siRNA (Human) - CRH0341 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SERCA1 ATPase RNAi - H00000487-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ATP2A1 - MBS8239361 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Atp2a1 (NM_173201.3) - SHH242602 from Creative biogene

Category siRNA
Species Reactivities Human

ATP2A1 shRNA Plasmid (Human) - CHH0341 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ATP2A1 miRNA 3'UTR clone - MiUTR3H-00219 from Creative biogene

Species Reactivities Human

ATP2A1 miRNA 3'UTR clone - MiUTR3H-00220 from Creative biogene

Species Reactivities Human
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