FCGR1A

Gene Symbol FCGR1A
Entrez Gene 2209
Alt Symbol CD64, CD64A, FCRI, IGFR1
Species Human
Gene Type protein-coding
Description Fc fragment of IgG, high affinity Ia, receptor (CD64)
Other Description Fc fragment of IgG, high affinity Ia, receptor for (CD64)|Fc gamma receptor|Fc-gamma RI|Fc-gamma receptor I A1|IgG Fc receptor I|fc-gamma RIA|fcgammaRIa|high affinity immunoglobulin gamma Fc receptor I
Swissprots Q92495 Q92663 P12314 Q5QNW7 P12315
Accessions AAA35678 AAA58414 AAD13842 CAI12556 CAI12557 P12314 AK291451 BAF84140 AK291502 BAF84191 BC032634 AAH32634 BC152383 AAI52384 DC320241 DQ786309 DQ890842 ABM81768 DQ893997 ABM84923 L03418 AAA36049 X14355 CAA32536 X14356 CAA32537 XM_005244957 XP_005245014 XM_005244958 XP_005245015 NM_000566 NP_000557
Function High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. {ECO:0000269|PubMed:10397749, ECO:0000269|PubMed:10514529, ECO:0000269|PubMed:21965667, ECO:0000269|PubMed:8611682, ECO:0000269|PubMed:9881690}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12756162, ECO:0000269|PubMed:8611682}; Single-pass type I membrane protein {ECO:0000269|PubMed:12756162, ECO:0000269|PubMed:8611682}. Note=Stabilized at the cell membrane through interaction with FCER1G.
Tissue Specificity Monocyte/macrophage specific.
Top Pathways Phagosome, Staphylococcus aureus infection, Leishmaniasis, Osteoclast differentiation, Fc gamma R-mediated phagocytosis

CD64 (N-19) - sc-7642 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD64 (N-19): sc-7642. Western blot analysis of CD64 expression in HL-60 (A) and RAW 264.7 (B) whole cell lysates.

CD64 (H-250) - sc-15364 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD64 (H-250): sc-15364. Western blot analysis of CD64 expression in non-transfected: sc-117752 (A) and human CD64 transfected: sc-115162 (B) 293T whole cell lysates.

CD64 (R-16) - sc-31215 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD64 (E-20) - sc-31218 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD64 (E-20): sc-31218. Western blot analysis of CD64 expression in non-transfected 293: sc-110760 (A), human CD64 transfected 293: sc-175234 (B) and RAW 264.7 (C) whole cell lysates.

CD64 (S-15) - sc-31216 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD64 (10.1) - sc-1184 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD64 (10.1): sc-1184. Immunofluorescence staining of methanol-fixed THP-1 cells showing membrane staining.

CD64 (A-16) - sc-31219 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CD64 [10.1] antibody (PE/Cy5®) - ab192338 from Abcam

Prices $370.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 10.1

Anti-CD64 [10.1] antibody (PerCP/Cy5.5®) - ab192340 from Abcam

Prices $370.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 10.1

Anti-CD64 [10.1] antibody, prediluted (Alexa Fluor® 647) - ab192343 from Abcam

Prices $370.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 10.1

Anti-CD64 antibody - ab95244 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CD64 antibody (ab95244) at 1/100 dilution + CEM cell line lysate at 35 µg

Anti-CD64 antibody [10.1] - ab119843 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10.1
Overlay histogram showing THP1 cells stained with ab119843 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab119843, 1µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed. This antibody gave a positive result in 80% methanol (5 min) fixed THP1 cells used under the same conditions.Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.

Anti-CD64 antibody [10.1] - ab23351 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 10.1
Overlay histogram showing THP1 cells stained with ab23351(red line). The cells were fixed with 4% paraformaldehyde (10 min) and incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab23351, 1µg/1x106 cells) for 30 min at 22°C. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1](ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.

Anti-CD64 antibody [10.1] (Allophycocyanin) - ab124529 from Abcam

Prices $372.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 10.1

Anti-CD64 antibody [10.1] (Biotin) - ab27928 from Abcam

Prices $372.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 10.1

Anti-CD64 antibody [10.1] (FITC) - ab93500 from Abcam

Prices $189.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 10.1
Staining of normal Human peripheral blood cells with FITC Mouse IgG1, K Isotype Control (open histogram) or ab93500. Cells in the monocyte gate were used for analysis.

Anti-CD64 antibody [10.1] (FITC) - ab34224 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10.1

Anti-CD64 antibody [10.1] (Phycoerythrin) - ab23890 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 10.1

Anti-CD64 antibody [10.1] - Low endotoxin, Azide free - ab185738 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 10.1

Anti-CD64 antibody [3D3] - ab140779 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3D3
All lanes : Anti-CD64 antibody [3D3] (ab140779) at 1/4000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cells transfected with pCMV6-ENTRY CD64 cDNALysates/proteins at 5 µg per lane.

Anti-FCGR1A antibody - ab104273 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-FCGR1A antibody (ab104273) at 1/100 dilution + NCI-H460 cell lysate at 35 µg

Anti-FCGR1A antibody - ab171824 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-FCGR1A antibody (ab171824) at 1 µg/mlLane 1 : FCGR1A-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-FCGR1A antibody [10.1] - ab201313 from Abcam

Prices $359.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 10.1

Anti-FCGR1A antibody [10.1] (FITC) - ab119828 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 10.1

Anti-FCGR1A antibody [10.1] (PE/Cy7 ®) - ab201318 from Abcam

Prices $359.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 10.1
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