Vav3

Gene Symbol Vav3
Entrez Gene 57257
Alt Symbol A530094I06Rik, AA986410, Idd18.1
Species Mouse
Gene Type protein-coding
Description vav 3 oncogene
Other Description VAV-3|guanine nucleotide exchange factor VAV3
Swissprots Q9R0C8 Q7TS85 Q8R076 Q8CCF5 A2CFD7 Q8BRV2 Q9JLS6
Accessions EDL01995 EDL01996 Q9R0C8 AF067816 AAF09171 AF140280 AAF20330 AK033253 BAC28212 AK041249 BAC30879 AK147053 BAE27637 AK150727 AK157057 BC027242 AAH27242 BC052739 AAH52739 XM_006501819 XP_006501882 XM_006501820 XP_006501883 XM_006535364 XP_006535427 XM_006535365 XP_006535428 NM_020505 NP_065251 NM_146139 NP_666251
Function Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not af
Tissue Specificity Abundantly expressed in osteoclasts and mature osteoblasts. Also expressed in bone marrow macrophages (at protein level):.
Top Pathways Focal adhesion, Leukocyte transendothelial migration, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, B cell receptor signaling pathway

VAV3 Polyclonal Antibody - bs-4286R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-VAV3 Polyclonal Antibody, Unconjugated (bs-4286R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

VAV3 Antibody (OABF01437) - OABF01437 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 antibody (Tyr173) - 70R-34662 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

VAV3 antibody - 70R-34663 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-4286R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-4286R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-4286R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-4286R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, Cy3 Conjugated - bs-4286R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, Cy5 Conjugated - bs-4286R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, Cy5.5 Conjugated - bs-4286R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, Cy7 Conjugated - bs-4286R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, FITC Conjugated - bs-4286R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, Biotin Conjugated - bs-4286R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, HRP Conjugated - bs-4286R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 antibody - AP32590PU-N from Acris Antibodies

Prices $350.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Lysates from untransfected (lane 1) and mouse Vav3-transfected Jurkat cells (lane 2) were probed with anti-Vav3.

Phospho-VAV3 (Tyr173) Polyclonal Antibody - 44-488 from Thermo Fisher Scientific

Prices $309.00
Sizes 10 blots
Host Rabbit
Clonality Polyclonal
Vav3 [pY173] phosphospecific antibody. Cos7 cells over-expressing murine Vav3 were serum starved and left untreated (1) or treated (2-5) with EGF were incubated with Vav3 [pY173] antibody following prior incubation with: no peptide (1, 2), the non-phospho immunogen (3), a generic [pY] peptide (4), or, the phosphopeptide immunogen (5). Data demonstrate antibody specificity.

Anti-Vav3 Antibody, mouse - 07-465 from Sigma-Aldrich

Prices $289.00
Sizes 07-465
Clonality Polyclonal
WB: Lysates from untransfected (lane 1) and mouse Vav3-transfected Jurkat cells (lane 2) were probed with anti-Vav3.

VAV3 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated - bs-4286R-A594 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated - bs-4286R-A680 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody, ALEXA FLUOR® 750 Conjugated - bs-4286R-A750 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody Cy3 Conjugated - C05273Cy3 from Signalway Antibody

Prices $409.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody Cy5 Conjugated - C05273Cy5 from Signalway Antibody

Prices $409.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody Cy5.5 Conjugated - C05273Cy5.5 from Signalway Antibody

Prices $409.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VAV3 Polyclonal Antibody Cy7 Conjugated - C05273Cy7 from Signalway Antibody

Prices $409.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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