ANO1

Gene Symbol	ANO1
Entrez Gene	55107
Alt Symbol	DOG1, ORAOV2, TAOS2, TMEM16A
Species	Human
Gene Type	protein-coding
Description	anoctamin 1, calcium activated chloride channel
Other Description	Ca2+-activated Cl- channel|anoctamin-1|discovered on gastrointestinal stromal tumors protein 1|oral cancer overexpressed 2|transmembrane protein 16A (eight membrane-spanning domains)|tumor-amplified and overexpressed sequence 2
Swissprots	Q5XXA6 Q8IYY8 A8KAM3 Q8N7V3
Accessions	EAW74757 EAW74758 EAW74759 Q5XXA6 AB845669 BAO49755 AI694083 AK001123 BAA91513 AK097619 BAC05123 AK293088 BAF85777 AK303971 BAH14087 AL833582 AY728143 AAU82085 BC027590 AAH27590 BC033036 AAH33036 CF593428 DB445158 DB450993 HQ418153 ADP09411 XM_006718602 XP_006718665 XM_006718604 XP_006718667 XM_006718605 XP_006718668 XM_011545121 XP_011543423 XM_011545122 XP_011543424 XM_011545123 XP_011543425 XM_011545124 XP_011543426 XM_011545125 XP_011543427 XM_011545126 XP_011543428 XM_011545127 XP_011543429 XM_011545128 XP_011543430 XM_011545129 XP_011543431 XM_011545130 XP_011543432 XM_011545131 XP_011543433 NM_018043 NP_060513 NR_030691
Function	Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:21984732, ECO:0000269|PubMed:22178883, ECO:0000269|PubMed:22946059}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors.
Tissue Specificity	Broadly expressed with higher levels in liver, skeletal muscle and gastrointestinal muscles. {ECO:0000269|PubMed:15215166, ECO:0000269|PubMed:16906560}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Anoctamin-1 (ANO1), Human, ELISA Kit - E01A1526 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/ml

Anoctamin 1 (ANO1), ELISA Kit - MBS7204353 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin 1 (ANO1), ELISA Kit - MBS9302486 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5.0pg/ml. Range 31.2pg/ml-1000pg/ml.

anoctamin 1, calcium activated chloride channel, ELISA Kit - MBS9330375 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin-1 (ANO1), ELISA Kit - MBS7253513 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin-1 (ANO1), ELISA Kit - MBS7232284 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin-1 (ANO1), ELISA Kit - MBS7215398 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin-1 (ANO1), ELISA Kit - MBS7235637 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin-1 (ANO1), ELISA Kit - MBS7231293 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin-1 (ANO1), ELISA Kit - MBS7222649 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin-1 (ANO1), ELISA Kit - MBS7233413 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin-1 (ANO1), ELISA Kit - MBS7252112 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin-1 (ANO1), ELISA Kit - MBS7237337 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin-1 (ANO1), ELISA Kit - MBS7206898 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/mL.

Anoctamin-1 (ANO1), ELISA Kit - MBS7232500 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human ANO1 ELISA Kit - E002450 from Biobool Category ELISA Kit

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