| Gene Symbol |
TXNDC12
|
| Entrez Gene |
51060
|
| Alt Symbol |
AG1, AGR1, ERP16, ERP18, ERP19, PDIA16, TLP19, hAG-1, hTLP19
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thioredoxin domain containing 12 (endoplasmic reticulum)
|
| Other Description |
ER protein 18|ER protein 19|anterior gradient homolog 1|endoplasmic reticulum protein ERp19|endoplasmic reticulum resident protein 18|endoplasmic reticulum resident protein 19|endoplasmic reticulum thioredoxin superfamily member, 18 kDa|protein disulfide isomerase family A, member 16|thioredoxin domain-containing protein 12|thioredoxin-like protein p19
|
| Swissprots |
Q96H50 Q5T1T4 O95881 B3KQS0
|
| Accessions |
CAI72102 EAX06800 O95881 AF131758 AAD20035 AF543416 AAN34781 AK056169 AK075409 BAG52132 AY358982 AAQ89341 BC001493 AAH01493 BC008913 AAH08913 BC008953 AAH08953 DA277685 FY213077 HQ448666 ADQ33144 NM_015913 NP_056997 NR_046405 NR_046406
|
| Function |
Possesses significant protein thiol-disulfide oxidase activity. {ECO:0000269|PubMed:12761212}.
|
| Subcellular Location |
Endoplasmic reticulum lumen {ECO:0000269|PubMed:12761212}.
|
| Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:14557066}.
|
| Top Pathways |
Glutathione metabolism
|
![Western Blot: TXNDC12 Overexpression Lysate (Adult Normal) [NBL1-17465] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TXNDC12.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3708_TXNDC12%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17465-img0002.jpg)
![Western Blot: AIF/AIFM1 Overexpression Lysate (Adult Normal) [NBP2-10578] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for AIF/AIFM1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6811_AIF-AIFM1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10578-img0001.jpg)