TXNDC12

Gene Symbol TXNDC12
Entrez Gene 51060
Alt Symbol AG1, AGR1, ERP16, ERP18, ERP19, PDIA16, TLP19, hAG-1, hTLP19
Species Human
Gene Type protein-coding
Description thioredoxin domain containing 12 (endoplasmic reticulum)
Other Description ER protein 18|ER protein 19|anterior gradient homolog 1|endoplasmic reticulum protein ERp19|endoplasmic reticulum resident protein 18|endoplasmic reticulum resident protein 19|endoplasmic reticulum thioredoxin superfamily member, 18 kDa|protein disulfide isomerase family A, member 16|thioredoxin domain-containing protein 12|thioredoxin-like protein p19
Swissprots Q96H50 Q5T1T4 O95881 B3KQS0
Accessions CAI72102 EAX06800 O95881 AF131758 AAD20035 AF543416 AAN34781 AK056169 AK075409 BAG52132 AY358982 AAQ89341 BC001493 AAH01493 BC008913 AAH08913 BC008953 AAH08953 DA277685 FY213077 HQ448666 ADQ33144 NM_015913 NP_056997 NR_046405 NR_046406
Function Possesses significant protein thiol-disulfide oxidase activity. {ECO:0000269|PubMed:12761212}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000269|PubMed:12761212}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:14557066}.
Top Pathways Glutathione metabolism

ERp19 (C-7) - sc-376410 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ERp19 (C-7): sc-376410. Western blot analysis of ERp19 expression in HeLa whole cell lysate.

ERp19 (H-142) - sc-134830 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ERp19 (H-142): sc-134830. Western blot analysis of ERp19 expression in HeLa whole cell lysate.

ERp19 (N-14) - sc-49653 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ERp19 (Q-20) - sc-49655 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ERp19 (Q-20): sc-49655. Western blot analysis of ERp19 expression in non-transfected: sc-110760 (A) and mouse ERp19 transfected: sc-110718 (B) 293 whole cell lysates.

Anti-AIF antibody - ab1998 from Abcam

Prices $401.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AIF antibody (ab1998) at 1 µg/mlLane 1 : K562 cell lysate Lane 2 : Rat heart tissue lysateLane 3 : Mouse heart tissue lysate

Anti-AIF antibody - ab140714 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human kidney (tubules) tissue labelling AIF at 5 µg/ml.

Anti-AIF antibody - ab87307 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AIF antibody (ab87307) at 1/250 dilutionLane 1 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell LysateLane 2 : Liver (Human) Tissue Lysate - adult normal tissue (ab29889)Lane 3 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 4 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-AIF antibody - ab1999 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-AIF antibody (ab1999) at 1 µg/ml + K562 cell lysate

Anti-AIF antibody - ab2086 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AIF antibody (ab2086) at 1 µg/mlLane 1 : K562 cell lysate Lane 2 : Mouse liver tissue lysateLane 3 : Rat liver tissue lysate

Anti-AIF antibody - ab89583 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-AIF antibody (ab89583) at 1 µg/ml + Human liver tissue lysate at 50 µg

Anti-AIF antibody - ab69646 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AIF antibody (ab69646) at 1/500 dilutionLane 1 : Jurkat cell extractLane 2 : HepG2 cell extractLane 3 : HUVEC cell extractLane 4 : HeLa cell extractLane 5 : HeLa cell extract with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-AIF antibody [1022-5] (Biotin) - ab51674 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1022-5

Anti-AIF antibody [4E7] - ab119917 from Abcam

Prices $387.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4E7
ELISA image showing use of ab119917.

Anti-AIF antibody [7F7AB10] - ab110327 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7F7AB10
Anti-AIF antibody [7F7AB10] (ab110327) at 5 µg/ml + Isolated mitochondria from Human heart at 5 µg

Anti-AIF antibody [7F7AB10] (Alexa Fluor® 488) - ab198313 from Abcam

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7F7AB10
ab198313 staining AIF in HeLa cells. The cells were fixed with 4% formaldehyde (10 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab198313 at 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at 1/250 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in HeLa cells fixed with 100% methanol (5min).

Anti-AIF antibody [7F7AB10] (Alexa Fluor® 647) - ab198055 from Abcam

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7F7AB10
ab198055 staining AIF in HeLa cells. The cells were fixed with 4% formaldehyde (10 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab198055 at a 1/50 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at a 1/250 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in HeLa cells fixed with 100% methanol (5 min).

Anti-AIF antibody [7F7AB10] (HRP) - ab198314 from Abcam

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7F7AB10
Anti-AIF antibody [7F7AB10] (HRP) (ab198314) at 1/5000 dilution + Human Heart Mitochondrial lysate (ab110337) at 10 µgdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-AIF antibody [E20] - Mitochondrial Marker - ab32516 from Abcam

Prices $403.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone E20
Anti-AIF antibody [E20] - Mitochondrial Marker (ab32516) at 1/1000 dilution + K562 cell lysate

Anti-AIF antibody [E20] - Mitochondrial Marker (Alexa Fluor® 647) - ab196847 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone E20
ab196847 staining AIF in HACAT cells. The cells were fixed with 4% formaldehyde (10 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 10% normal goat serum in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab196847 at 1/200 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at 1/200 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-AIF antibody [E20] - Mitochondrial Marker (Biotin) - ab197526 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone E20
IHC image of AIF staining in a section of formalin-fixed paraffin-embedded Hu_Colon_Norm*, performed on a Leica Bond system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab197526 at 1/100 dilution for 15 mins at room temperature and detected using an HRP conjugated ABC system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. The inset negative control image is taken from an identical assay without primary antibody.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.*Tissue obtained from the Human Research Tissue Bank, supported by the NIHR Cambridge Biomedical Research Centre

Anti-ERp19 antibody - ab104170 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ERp19 antibody (ab104170) at 1/100 dilution + Y79 cell lysate at 35 µg

Anti-ERp19 antibody [EPR9024] - ab134938 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9024
All lanes : Anti-ERp19 antibody [EPR9024] (ab134938) at 1/1000 dilutionLane 1 : Human placenta lysateLane 2 : 293T cell lysateLane 3 : HepG2 cell lysateLane 4 : Y79 cell lysateLysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilutiondeveloped using the ECL technique

Anti-ERp19 antibody [EPR9025] - ab137035 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9025
All lanes : Anti-ERp19 antibody [EPR9025] (ab137035) at 1/10000 dilutionLane 1 : 293T lysateLane 2 : HepG2 lysateLane 3 : Y79 lysateLane 4 : Human fetal kidney lysatesLysates/proteins at 10 µg per lane.SecondaryHRP conjugated Goat anti Rabbit IgG at 1/2000 dilution

Anti-TXNDC12 Antibody (aa140-170, AP) - LS-C242332 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TXNDC12 Antibody (aa140-170, Biotin) - LS-C242333 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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