ARF1

Gene Symbol ARF1
Entrez Gene 375
Alt Symbol -
Species Human
Gene Type protein-coding
Description ADP-ribosylation factor 1
Other Description -
Swissprots P84077
Accessions AAA35511 EAW69831 EAW69832 EAW69833 EAW69834 EAW69835 EAW69836 P84077 AF052179 AAC28623 AF055002 AAC09356 AF493881 AAM12595 AK000620 AK057838 AK057875 AK130737 AK293553 BAG57030 AK296020 BAG58790 AK297792 BAG60132 AM393261 CAL38139 AM393462 CAL38339 AM393595 CAL38472 AM393712 CAL38588 BC009247 AAH09247 BC010415 BC010429 AAH10429 BC011358 AAH11358 BF337061 BG421840 BM353046 BM844480 BQ935470 BQ949763 BT007393 AAP36057 M36340 AAA35552 M84326 AAA35512 NM_001024226 NP_001019397 NM_001024227 NP_001019398 NM_001024228 NP_001019399 NM_001658 NP_001649
Function GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).
Subcellular Location Golgi apparatus {ECO:0000269|PubMed:17555535}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:17555535}. Cell junction, synapse, synaptosome {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}.
Top Pathways Vibrio cholerae infection, Endocytosis, Legionellosis

Human-ARF1-cDNA-Clone - DC02602 from Abgent, a WuXi AppTec company

Prices $244.35
Sizes 10 µg
Species Human
Accession BC009247

ARF1 - MBS1268343 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC009247

Human ARF1 cDNA clone(NM_001024226.1) - CDFH001036 from Creative Biomart

Species Human
Accession NM_001024226.1

Human ARF1 cDNA clone(NM_001024227.1) - CDFH001037 from Creative Biomart

Species Human
Accession NM_001024227.1

Human ARF1 cDNA clone(NM_001024228.1) - CDFH001038 from Creative Biomart

Species Human
Accession NM_001024228.1

Human ARF1 cDNA clone(NM_001024227.1) - CDFH001039 from Creative Biomart

Species Human
Accession NM_001024227.1

Human ARF1 cDNA clone(NM_001658.3) - CDFH001040 from Creative Biomart

Species Human
Accession NM_001658.3

Human ARF1 cDNA clone(NM_001658.3) - CDFH001041 from Creative Biomart

Species Human
Accession NM_001658.3

Human ARF1 ORF Clone(NM_001658.3) - CDCL154224 from Creative Biomart

Species Human
Accession NM_001658.3

Human ARF1 ORF Clone(NM_001658.3) - CDCR280871 from Creative Biomart

Species Human
Accession NM_001658.3

Human ARF1 ORF Clone(NM_001658.3) - CDCR280872 from Creative Biomart

Species Human
Accession NM_001658.3

Human ARF1 ORF Clone(NM_001658.3) - CDCR280873 from Creative Biomart

Species Human
Accession NM_001658.3

Human ARF1 ORF Clone(NM_001024226.1) - CDCR342162 from Creative Biomart

Species Human
Accession NM_001024226.1

Human ARF1 ORF Clone(NM_001024226.1) - CDCR342163 from Creative Biomart

Species Human
Accession NM_001024226.1

Human ARF1 ORF Clone(NM_001024226.1) - CDCR342164 from Creative Biomart

Species Human
Accession NM_001024226.1

Human ARF1 ORF Clone(NM_001024227.1) - CDCR342165 from Creative Biomart

Species Human
Accession NM_001024227.1

Human ARF1 ORF Clone(NM_001024227.1) - CDCR342166 from Creative Biomart

Species Human
Accession NM_001024227.1

Human ARF1 ORF Clone(NM_001024228.1) - CDCR342167 from Creative Biomart

Species Human
Accession NM_001024228.1

Human ARF1 ORF Clone(NM_001024228.1) - CDCR342168 from Creative Biomart

Species Human
Accession NM_001024228.1
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