| Gene Symbol |
Klrb1c
|
| Entrez Gene |
17059
|
| Alt Symbol |
AI462337, CD161, Ly-59, Ly55c, Ly59, NK-RP1, NK1.1, NKR-P1.9, NKRP1, NKRP140, Nk-1, Nk-1.2, Nk1, Nk1.2, Nkrp1c, ly-55c
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
killer cell lectin-like receptor subfamily B member 1C
|
| Other Description |
CD161 antigen-like family member C|NKR-P1 40|killer cell lectin-like receptor subfamily A member 1C|lymphocyte antigen 55 complex, locus C|lymphocyte antigen 55c|lymphocyte antigen 59|natural killer cell receptor protein NKR-P1C|natural killer cell receptor-P1|natural killer cell surface protein P1-40|natural killer cell-associated antigen 1
|
| Swissprots |
Q541U5 P27814 Q925G3
|
| Accessions |
AAG02283 AAP82935 ABC71750 AFI61945 AFK08668 EDK99901 P27814 AF354263 AAK39103 AK079743 BAC37739 AK136745 BC061168 AAH61168 DQ237929 ABB72027 HQ713434 AEP22554 M77678 AAA39824 S43141 AAB22979 X64720 CAA45973 XM_011238032 XP_011236334 NM_001159904 NP_001153376 NM_008527 NP_032553
|
| Function |
Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production. {ECO:0000269|PubMed:12813047, ECO:0000269|PubMed:15814704}.
|
| Subcellular Location |
Membrane; Single-pass type II membrane protein.
|
| Tissue Specificity |
Expressed in natural killer cells.
|
| Top Pathways |
Natural killer cell mediated cytotoxicity
|