Gene Symbol | Klrb1c |
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Entrez Gene | 17059 |
Alt Symbol | AI462337, CD161, Ly-59, Ly55c, Ly59, NK-RP1, NK1.1, NKR-P1.9, NKRP1, NKRP140, Nk-1, Nk-1.2, Nk1, Nk1.2, Nkrp1c, ly-55c |
Species | Mouse |
Gene Type | protein-coding |
Description | killer cell lectin-like receptor subfamily B member 1C |
Other Description | CD161 antigen-like family member C|NKR-P1 40|killer cell lectin-like receptor subfamily A member 1C|lymphocyte antigen 55 complex, locus C|lymphocyte antigen 55c|lymphocyte antigen 59|natural killer cell receptor protein NKR-P1C|natural killer cell receptor-P1|natural killer cell surface protein P1-40|natural killer cell-associated antigen 1 |
Swissprots | Q541U5 P27814 Q925G3 |
Accessions | AAG02283 AAP82935 ABC71750 AFI61945 AFK08668 EDK99901 P27814 AF354263 AAK39103 AK079743 BAC37739 AK136745 BC061168 AAH61168 DQ237929 ABB72027 HQ713434 AEP22554 M77678 AAA39824 S43141 AAB22979 X64720 CAA45973 XM_011238032 XP_011236334 NM_001159904 NP_001153376 NM_008527 NP_032553 |
Function | Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production. {ECO:0000269|PubMed:12813047, ECO:0000269|PubMed:15814704}. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Expressed in natural killer cells. |
Top Pathways | Natural killer cell mediated cytotoxicity |
CD161 CRISPR/Cas9 KO Plasmid (m) - sc-421491 from Santa Cruz Biotechnology
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CD161 HDR Plasmid (m) - sc-421491-HDR from Santa Cruz Biotechnology
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CD161 Double Nickase Plasmid (m) - sc-421491-NIC from Santa Cruz Biotechnology
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CD161 Double Nickase Plasmid (m2) - sc-421491-NIC-2 from Santa Cruz Biotechnology
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CD161 CRISPR Activation Plasmid (m) - sc-421491-ACT from Santa Cruz Biotechnology
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CD161 CRISPR Activation Plasmid (m2) - sc-421491-ACT-2 from Santa Cruz Biotechnology
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CD161 Lentiviral Activation Particles (m) - sc-421491-LAC from Santa Cruz Biotechnology
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CD161 Lentiviral Activation Particles (m2) - sc-421491-LAC-2 from Santa Cruz Biotechnology
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CD161 siRNA (m) - sc-72139 from Santa Cruz Biotechnology
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CD161 shRNA Plasmid (m) - sc-72139-SH from Santa Cruz Biotechnology
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CD161 shRNA (m) Lentiviral Particles - sc-72139-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN34432 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34432 from Sigma-Aldrich
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KLRB1C siRNA (Mouse) - CRM2402 from Cohesion Biosciences
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shRNA set against Mouse Klrb1c (NM_008527.2) - SHH326795 from Creative biogene
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Mouse KLRB1C siRNA - orb281878 from Biorbyt
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KLRB1C shRNA Plasmid (Mouse) - CHM2402 from Cohesion Biosciences
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