Gene Symbol |
Stmn1
|
Entrez Gene |
16765
|
Alt Symbol |
19k, Lag, Lap18, Op18, P18, P19, Pig, Pp17, Pp18, Pp19, Pr22, Smn
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
stathmin 1
|
Other Description |
leukemia associated phosphoprotein p18|leukemia-associated gene protein|leukemia-associated phosphoprotein p18|metablastin|oncoprotein 18|phosphoprotein p19|prosolin|stathmin
|
Swissprots |
P54227
|
Accessions |
EDL30008 EDL30009 P54227 AB064953 BAB61894 AK002606 BAB22225 AK012231 BAB28109 AK012347 BAB28178 AK013302 BAB28778 AK014108 BAB29161 AK088251 AK088628 BAC40463 BC010581 AAH10581 BC031831 AAH31831 BC054396 AAH54396 X94915 CAA64401 NM_019641 NP_062615
|
Function |
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser- 16 may be required for axon formation during neurogenesis (By similarity). Involved in the control of the learned and innate fear. {ECO:0000250, ECO:0000269|PubMed:16286011}.
|
Subcellular Location |
Cytoplasm, cytoskeleton.
|
Tissue Specificity |
Highly expressed in the lateral nucleus of the amygdala. {ECO:0000269|PubMed:16286011}.
|
Top Pathways |
MAPK signaling pathway, MicroRNAs in cancer
|