Gene Symbol | Stmn1 |
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Entrez Gene | 16765 |
Alt Symbol | 19k, Lag, Lap18, Op18, P18, P19, Pig, Pp17, Pp18, Pp19, Pr22, Smn |
Species | Mouse |
Gene Type | protein-coding |
Description | stathmin 1 |
Other Description | leukemia associated phosphoprotein p18|leukemia-associated gene protein|leukemia-associated phosphoprotein p18|metablastin|oncoprotein 18|phosphoprotein p19|prosolin|stathmin |
Swissprots | P54227 |
Accessions | EDL30008 EDL30009 P54227 AB064953 BAB61894 AK002606 BAB22225 AK012231 BAB28109 AK012347 BAB28178 AK013302 BAB28778 AK014108 BAB29161 AK088251 AK088628 BAC40463 BC010581 AAH10581 BC031831 AAH31831 BC054396 AAH54396 X94915 CAA64401 NM_019641 NP_062615 |
Function | Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser- 16 may be required for axon formation during neurogenesis (By similarity). Involved in the control of the learned and innate fear. {ECO:0000250, ECO:0000269|PubMed:16286011}. |
Subcellular Location | Cytoplasm, cytoskeleton. |
Tissue Specificity | Highly expressed in the lateral nucleus of the amygdala. {ECO:0000269|PubMed:16286011}. |
Top Pathways | MAPK signaling pathway, MicroRNAs in cancer |
Op18 CRISPR/Cas9 KO Plasmid (m) - sc-421370 from Santa Cruz Biotechnology
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Op18 HDR Plasmid (m) - sc-421370-HDR from Santa Cruz Biotechnology
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Op18 Double Nickase Plasmid (m) - sc-421370-NIC from Santa Cruz Biotechnology
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Op18 Double Nickase Plasmid (m2) - sc-421370-NIC-2 from Santa Cruz Biotechnology
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Op18 CRISPR Activation Plasmid (m) - sc-421370-ACT from Santa Cruz Biotechnology
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Op18 CRISPR Activation Plasmid (m2) - sc-421370-ACT-2 from Santa Cruz Biotechnology
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Op18 Lentiviral Activation Particles (m) - sc-421370-LAC from Santa Cruz Biotechnology
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Op18 Lentiviral Activation Particles (m2) - sc-421370-LAC-2 from Santa Cruz Biotechnology
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Op18 siRNA (m) - sc-36128 from Santa Cruz Biotechnology
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Op18 shRNA Plasmid (m) - sc-36128-SH from Santa Cruz Biotechnology
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Op18 shRNA (m) Lentiviral Particles - sc-36128-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU095351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN42209 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42209 from Sigma-Aldrich
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STMN1 siRNA (Mouse) - CRM2288 from Cohesion Biosciences
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STMN1 - MBS8229681 from MyBioSource
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shRNA set against Mouse STMN1 (NM_019641.4) - SHH419936 from Creative biogene
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Mouse STMN1 siRNA - orb281764 from Biorbyt
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STMN1 shRNA Plasmid (Mouse) - CHM2288 from Cohesion Biosciences
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