IL1B

Gene Symbol	IL1B
Entrez Gene	3553
Alt Symbol	IL-1, IL1-BETA, IL1F2
Species	Human
Gene Type	protein-coding
Description	interleukin 1, beta
Other Description	IL-1 beta|catabolin|interleukin-1 beta|preinterleukin 1 beta|pro-interleukin-1-beta
Swissprots	Q53X59 P01584 Q9UCT6 Q7RU01 Q7M4S7 Q96HE5 Q53XX2
Accessions	AAA74137 AAM88883 AAX88888 CAA28185 CAD29872 CCA63968 EAW73605 EAW73606 EAW73607 P01584 AB451494 BAG70308 AF043335 AAC03536 AK313983 BC008678 AAH08678 BT007213 AAP35877 CR407679 CAG28607 DQ890673 ABM81599 DQ893854 ABM84780 K02770 AAA36106 M15330 AAA59135 M54933 AAA59136 X02532 CAA26372 X56087 CAA39567 XM_006712496 XP_006712559 NM_000576 NP_000567
Function	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. {ECO:0000269|PubMed:3920526}.
Subcellular Location	Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Top Pathways	Herpes simplex infection, Tuberculosis, Legionellosis, TNF signaling pathway, Salmonella infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human IL1 beta full length protein - ab155616 from Abcam Category Protein Prices $192.00 Sizes 10 µg Source E. coli Species Human

Active human IL1 beta full length protein - ab157280 from Abcam Category Protein Prices $239.00 Sizes 10 µg Source E. coli Species Human

Active human IL1 beta full length protein - ab9617 from Abcam Category Protein Prices $110.00, $257.00 Sizes 2 µg, 10 µg Source E. coli Species Human

Active human IL1 beta protein fragment - ab73577 from Abcam Category Protein Prices $257.00 Sizes 10 µg Source E. coli Species Human

Active human IL1B full length protein - ab192141 from Abcam Category Protein Prices $192.00 Sizes 10 µg Source E. coli Species Human

Active mouse IL1 beta full length protein - ab9723 from Abcam Category Protein Prices $110.00, $257.00 Sizes 2 µg, 10 µg Source E. coli Species Mouse

Active mouse IL1 beta full length protein - ab192113 from Abcam Category Protein Prices $192.00 Sizes 10 µg Source E. coli Species Mouse

Active mouse IL1 beta protein fragment - ab73588 from Abcam Category Protein Prices $257.00 Sizes 10 µg Source E. coli Species Mouse

Active rat IL1 beta full length protein - ab200284 from Abcam Category Protein Prices $101.00 Sizes 2 µg Source E. coli Species Rat

Active rat IL1 beta full length protein - ab9788 from Abcam Category Protein Prices $110.00, $257.00 Sizes 2 µg, 10 µg Source E. coli Species Rat

Active rat IL1 beta full length protein - ab191754 from Abcam Category Protein Prices $192.00 Sizes 10 µg Source E. coli Species Rat

Active rat IL1 beta protein fragment - ab73589 from Abcam Category Protein Prices $257.00 Sizes 10 µg Source E. coli Species Rat

Active rhesus monkey IL1 beta full length protein - ab200283 from Abcam Category Protein Prices $101.00 Sizes 2 µg Source E. coli Species Monkey

Bottlenose Dolphin IL1 beta protein fragment - ab128517 from Abcam Category Protein Prices $235.00 Sizes 25 µg Source Saccharomyces cerevisiae Species Dolphin

Cat IL1 beta full length protein - ab87389 from Abcam Category Protein Prices $252.00 Sizes 25 µg Source Yeast Species Cat

Cow IL1 beta full length protein - ab88013 from Abcam Category Protein Prices $252.00 Sizes 25 µg Source Yeast Species Bovine

Dog IL1 beta full length protein - ab87391 from Abcam Category Protein Prices $252.00 Sizes 25 µg Source Yeast Species Dog

Guinea pig IL1 beta full length protein - ab117222 from Abcam Category Protein Prices $345.00 Sizes 25 µg Source Yeast Species Guinea Pig

Human IL1 beta full length protein - ab184595 from Abcam Category Protein Source Yeast Species Human

Human IL1 beta full length protein - ab53666 from Abcam Category Protein Source E. coli Species Human

Human IL1 beta peptide - ab104206 from Abcam Category Peptide

Human IL1 beta protein fragment - ab73581 from Abcam Category Protein Source E. coli Species Human

IL1 beta protein fragment - ab93084 from Abcam Category Protein Source Yeast

Mouse IL1 beta full length protein - ab128561 from Abcam Category Protein Source Yeast Species Mouse

Mouse IL1 beta full length protein - ab78839 from Abcam Category Protein Source E. coli Species Mouse

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