FADS2

Gene Symbol	FADS2
Entrez Gene	9415
Alt Symbol	D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13
Species	Human
Gene Type	protein-coding
Description	fatty acid desaturase 2
Other Description	delta(6) desaturase|delta(6) fatty acid desaturase|delta-6 desaturase|delta-6 fatty acid desaturase|delta-6-desaturase|linoleoyl-CoA desaturase (delta-6-desaturase)-like 2
Swissprots	A8K2M6 Q9H3G3 O95864 B7Z634 Q6MZQ7 Q96SV8 Q96H07 Q9Y3X4
Accessions	CAF86135 EAW73974 EAW73975 O95864 AA665550 AF084559 AAG23121 AF108658 AAG43192 AF126799 AAD20018 AK027459 BAG51327 AK027513 BAB55167 AK027577 BAG51351 AK074925 BAG52031 AK074939 BAC11305 AK074991 AK123240 BAG53882 AK290291 BAF82980 AK299762 BAH13120 AL050118 CAB43280 BC009011 AAH09011 DA233832 HY090295 XM_011545395 XP_011543697 NM_001281501 NP_001268430 NM_001281502 NP_001268431 NM_004265 NP_004256
Function	Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma- linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions. It catalizes as well the introduction of a cis double bond in palmitate to produce the mono-unsaturated fatty acid sapienate, the most abundant fatty acid in sebum. {ECO:0000269|PubMed:12713571, ECO:0000269|PubMed:9867867}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in a wide array of tissues, highest expression is found in liver followed by brain, lung, heart, and retina. A lower level is found in breast tumor when compared with normal tissues; lowest levels were found in patients with poor prognostic index. {ECO:0000269|PubMed:10860662, ECO:0000269|PubMed:12851727, ECO:0000269|PubMed:9867867}.
Top Pathways	PPAR signaling pathway, alpha-Linolenic acid metabolism, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Delta-6 Desaturase / FADS2 ELISA Kit (Sandwich ELISA) - LS-F7003 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 13.9 pg/ml Range 31.25-2000 pg/ml

Rat Delta-6 Desaturase / FADS2 ELISA Kit (Sandwich ELISA) - LS-F7004 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 1.56 ng/ml Range 31.25-2000 pg/ml

Human FADS2 ELISA Kit - abx151480 from Abbexa Category ELISA Kit Sensitivity 13.9 pg/ml Range 31.25 pg/ml - 2000 pg/ml

Fatty acid desaturase 2 (FADS2), Human, ELISA Kit - CSB-EL007960HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Fatty Acid Desaturase 2 (FADS2), Human, ELISA Kit - SEF417Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 2.8pg/mL Range 6.9-5,000pg/mL

Fatty acid desaturase 2, FADS2, Human, ELISA Kit - E0400h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

Human FADS2(Fatty Acid Desaturase 2) ELISA Kit - E-EL-H0372 from Elabscience Category ELISA Kit Sensitivity 46.88 pg/mL Range 78.13—5000 pg/mL

Human FADS2 (Fatty Acid Desaturase 2) CLIA Kit - E-CL-H0303 from Elabscience Category CLIA Kit Sensitivity 9.38 pg/mL Range Average Recovery (%)

FADS2, ELISA Kit - MBS2511882 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/mL Range 78.125--5000pg/mL

FADS2, ELISA Kit - MBS2515245 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156--10ng/mL

FADS2, ELISA Kit - MBS2509127 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/mL Range 78.125-5000pg/mL

FADS2, ELISA Kit - MBS2506582 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 23.438pg/mL Range 39.063-2500pg/mL

FADS2, ELISA Kit - MBS2500325 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.875pg/mL Range 3.125-200pg/mL

FADS2, ELISA Kit - MBS2503150 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 2.344pg/mL Range 3.906-250pg/mL

Fatty Acid Desaturase 2, ELISA Kit - MBS085536 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fatty Acid Desaturase 2, ELISA Kit - MBS048416 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

fatty acid desaturase 2, ELISA Kit - MBS930393 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human FADS2 is typically less than 7.8 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 31.2 pg/ml-2000 pg/ml.

Fatty Acid Desaturase 2, ELISA Kit - MBS066226 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/ml. Range 0.5 ng/ml - 16 ng/ml.

Fatty Acid Desaturase 2, ELISA Kit - MBS080611 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fatty Acid Desaturase 2, ELISA Kit - MBS059876 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fatty Acid Desaturase 2, ELISA Kit - MBS076005 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fatty Acid Desaturase 2, ELISA Kit - MBS049902 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Fatty Acid Desaturase 2 (FADS2) - SEF417Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 13.9pg/mL. Range 31.25-2000pg/mL The standard curve concentrations used for the ELISA’s were 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL

ELISA Kit for Fatty Acid Desaturase 2 (FADS2) - SEF417Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.66ng/mL. Range 1.56-100ng/mL The standard curve concentrations used for the ELISA’s were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL, 1.56ng/mL

Human Fatty acid desaturase 2(FADS2) ELISA kit - CSB-EL007960HU from Cusabio Category ELISA Kit Sensitivity 7.8pg/ml Range 31.2 pg/ml-2000 pg/ml

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