CHSY1

Gene Symbol CHSY1
Entrez Gene 22856
Alt Symbol CHSY, CSS1, ChSy-1, TPBS
Species Human
Gene Type protein-coding
Description chondroitin sulfate synthase 1
Other Description N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1|N-acetylgalactosaminyltransferase II|carbohydrate synthase 1|chondroitin glucuronyltransferase 1|chondroitin glucuronyltransferase II|chondroitin synthase 1|glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1
Swissprots Q9Y2J5 Q86X52 Q7LFU5 Q6UX38
Accessions EAX02292 Q86X52 AB023207 BAA76834 AB071402 BAB64936 AK075096 AK296943 BAG59492 AL137409 AY358529 AAQ88893 BC046247 AAH46247 BQ007796 XM_006720435 XP_006720498 XM_011521364 XP_011519666 XM_011521365 XP_011519667 NM_014918 NP_055733
Function Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling. {ECO:0000269|PubMed:11514575, ECO:0000269|PubMed:21129727}.
Subcellular Location Golgi apparatus, Golgi stack membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Secreted.
Tissue Specificity Ubiquitous, with the highest levels in placenta. Detected at low levels in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, adrenal gland, mammary gland, stomach, small intestine, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:11514575, ECO:0000269|PubMed:12907687}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

Human CHSY1 protein fragment - ab161443 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161443 on a 12.5% SDS-PAGE stained with Coomassie Blue.

CHSY1 Antibody Blocking Peptide - LS-E2546 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human CHSY1 Protein - H00022856-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CHSY1-Antibody-Center-Blocking-peptide - BP13586c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CHSY1 - H00022856-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

CHSY1 - H00022856-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

CHSY1 fusion protein - Ag5766 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human CHSY1, GST-tagged - CHSY1-11235H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Chondroitin sulfate synthase 1(CHSY1) ,partial - CSB-YP005416HU CSB-EP005416HU CSB-BP005416HU CSB-MP005416HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CHSY1 Recombinant Protein Antigen - NBP2-13838PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

CHSY1 Peptide, Human - M34GP03159H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Chondroitin sulfate synthase 1 (CHSY1), partial, Recombinant Protein - MBS1305418 from MyBioSource

Category Protein
Prices $845.00, $845.00, $1,070.00, $1,070.00, $1,195.00, $1,195.00, $1,640.00, $1,640.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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