Gene Symbol |
Atp6ap2
|
Entrez Gene |
70495
|
Alt Symbol |
(P)RR, 5730403E06Rik, APT6M8-9, ATP6M8-9, Atp6ip2, M8-9
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
ATPase, H+ transporting, lysosomal accessory protein 2
|
Other Description |
(pro)renin receptor|ATPase H(+)-transporting lysosomal-interacting protein 2|ATPase, H+ transporting, lysosomal interacting protein 1|ATPase, H+ transporting, lysosomal interacting protein 2|renin receptor|renin/prorenin receptor
|
Swissprots |
Q91YU5 A2BDN5 Q8BVU6 Q9CYN9
|
Accessions |
Q9CYN9 AB192471 BAE92936 AK017482 BAB30766 AK029405 BAC26436 AK076495 BAC36365 AK151735 AK168139 AK210696 AW475779 AW985491 BC014706 AAH14706 BY784908 NM_027439 NP_081715
|
Function |
Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity). {ECO:0000250}.
|
Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|