Gene Symbol | Atp6ap2 |
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Entrez Gene | 70495 |
Alt Symbol | (P)RR, 5730403E06Rik, APT6M8-9, ATP6M8-9, Atp6ip2, M8-9 |
Species | Mouse |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal accessory protein 2 |
Other Description | (pro)renin receptor|ATPase H(+)-transporting lysosomal-interacting protein 2|ATPase, H+ transporting, lysosomal interacting protein 1|ATPase, H+ transporting, lysosomal interacting protein 2|renin receptor|renin/prorenin receptor |
Swissprots | Q91YU5 A2BDN5 Q8BVU6 Q9CYN9 |
Accessions | Q9CYN9 AB192471 BAE92936 AK017482 BAB30766 AK029405 BAC26436 AK076495 BAC36365 AK151735 AK168139 AK210696 AW475779 AW985491 BC014706 AAH14706 BY784908 NM_027439 NP_081715 |
Function | Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Renin Receptor CRISPR/Cas9 KO Plasmid (m) - sc-427726 from Santa Cruz Biotechnology
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Renin Receptor HDR Plasmid (m) - sc-427726-HDR from Santa Cruz Biotechnology
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Renin Receptor Double Nickase Plasmid (m) - sc-427726-NIC from Santa Cruz Biotechnology
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Renin Receptor Double Nickase Plasmid (m2) - sc-427726-NIC-2 from Santa Cruz Biotechnology
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Renin Receptor CRISPR Activation Plasmid (m) - sc-427726-ACT from Santa Cruz Biotechnology
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Renin Receptor CRISPR Activation Plasmid (m2) - sc-427726-ACT-2 from Santa Cruz Biotechnology
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Renin Receptor Lentiviral Activation Particles (m) - sc-427726-LAC from Santa Cruz Biotechnology
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Renin Receptor Lentiviral Activation Particles (m2) - sc-427726-LAC-2 from Santa Cruz Biotechnology
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Renin Receptor siRNA (m) - sc-62935 from Santa Cruz Biotechnology
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Renin Receptor shRNA Plasmid (m) - sc-62935-SH from Santa Cruz Biotechnology
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Renin Receptor shRNA (m) Lentiviral Particles - sc-62935-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU003641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN27223 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27223 from Sigma-Aldrich
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ATP6AP2 siRNA (Mouse) - CRM8255 from Cohesion Biosciences
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ATP6AP2 - MBS827080 from MyBioSource
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shRNA set against Mouse ATP6AP2 (NM_027439.4) - SHH242970 from Creative biogene
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ATP6AP2 shRNA Plasmid (Mouse) - CHM8255 from Cohesion Biosciences
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