LPAR1

Gene Symbol	LPAR1
Entrez Gene	1902
Alt Symbol	EDG2, GPR26, Gpcr26, LPA1, Mrec1.3, VZG1, edg-2, rec.1.3, vzg-1
Species	Human
Gene Type	protein-coding
Description	lysophosphatidic acid receptor 1
Other Description	LPA receptor 1|LPA-1|endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2|lysophosphatidic acid receptor Edg-2|ventricular zone gene 1
Swissprots	P78351 O00722 B4DK36 O00656 Q92633
Accessions	CAC34034 CAE91525 EAW59068 EAW59069 Q92633 AK022808 BAG51118 AK290287 BAF82976 AK296374 BAG59048 AK298590 BAG60780 AK299279 BAG61296 AY322546 AAP84359 BC030615 AAH30615 BC036034 AAH36034 BC073167 AAH73167 BI461641 U78192 AAC00530 U80811 AAC51139 Y09479 CAA70686 XM_005251781 XP_005251838 XM_005251782 XP_005251839 NM_001401 NP_001392 NM_057159 NP_476500
Function	Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation. {ECO:0000269|PubMed:19306925}.
Subcellular Location	Cell surface {ECO:0000269|PubMed:19306925}. Cell membrane {ECO:0000269|PubMed:19306925}; Multi-pass membrane protein {ECO:0000269|PubMed:19306925}. Note=Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA colocalizes with RALA in the endocytic vesicles.
Tissue Specificity	Expressed in many adult organs, including brain, heart, colon, small intestine, placenta, prostate, ovary, pancreas, testes, spleen, skeletal muscle, and kidney. Little or no expression in liver, lung, thymus, or peripheral blood leukocytes.
Top Pathways	Gap junction, PI3K-Akt signaling pathway, Rap1 signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EDG2 peptide - ab184693 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

EDG2 peptide - ab94879 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human EDG2 full length protein - ab152354 from Abcam Category Protein Source Wheat germ Species Human

Human EDG2 protein fragment - ab152355 from Abcam Category Protein Source Wheat germ Species Human

Mouse EDG2 peptide - ab39781 from Abcam Category Peptide Species Mouse

GPR26 Antibody Blocking Peptide - LS-E28889 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR26 Antibody Blocking Peptide - LS-E28897 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR26 Antibody Blocking Peptide - LS-E29080 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

LPAR1 / LPA1 / EDG2 Antibody Blocking Peptide - LS-E8092 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LPAR1 / LPA1 / EDG2 Antibody Blocking Peptide - LS-E28497 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

LPAR1 / LPA1 / EDG2 Antibody Blocking Peptide - LS-E28506 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human LPAR1/LPA1/EDG-2 Protein - H00001902-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human LPAR1/LPA1/EDG-2 Protein - H00001902-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

LPAR1/LPA1/EDG-2 Peptide - P1746 from Novus Biologicals Category Peptide Species Human

EDG2-Antibody-N-term-Blocking-Peptide - BP6138a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

EDG2 / LPAR1 - H00001902-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

EDG2 / LPAR1 - H00001902-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

EDG2 / LPAR1 - H00001902-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

EDG2 / LPAR1 control peptide - SP5160CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

LPAR1,EDG2 fusion protein - Ag14253 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human LPAR1, GST-tagged - LPAR1-616H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Lysophosphatidic Acid Receptor 1 (LPAR1) - RPC569Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

ChemiSCREEN™ Membrane Preparation Recombinant Human LPA 1 Lysophospholipid Receptor - HTS089M from EMD Millipore Prices $596.00 Sizes 200 units Species Human

EDG-2 (W45) Peptide - BS2695P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Lysophosphatidic Acid Receptor 1 (LPAR1) - RPC569Hu01 from Cloud-clone Category Protein Source E.coli Species Human

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