JAG1

Gene Symbol	JAG1
Entrez Gene	182
Alt Symbol	AGS, AHD, AWS, CD339, HJ1, JAGL1
Species	Human
Gene Type	protein-coding
Description	jagged 1
Other Description	protein jagged-1
Swissprots	O15122 O14902 A0AV43 P78504 E9PCF9 Q15816 B4DYR1
Accessions	ACH41921 ACJ68516 ACJ68517 ACJ68518 EAX10341 P78504 AF003837 AAC51731 AF028593 AAB84053 AI268246 AK302554 BAG63823 AK312722 BAG35596 BC028007 BC098393 AAH98393 BC126205 AAI26206 BC126207 AAI26208 BF056748 HQ258535 ADR83289 U61276 AAB39007 U73936 AAC52020 U77720 AAC51323 U77914 AAC50909 Z50166 NM_000214 NP_000205
Function	Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro). {ECO:0000250, ECO:0000269|PubMed:18660822, ECO:0000269|PubMed:9462510}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells.
Top Pathways	Notch signaling pathway, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human JAG1 gene - orb92760 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human Jagged 1 (NP_000205) VersaClone cDNA - RDC0722 from R&D Systems Prices $799.00 Sizes 10 µg Species Human

JAG1 - MBS1273945 from MyBioSource Species Human Accession BC126205

Human JAG1 ORF clone(NM_000214.2) - CDCL185004 from Creative Biomart Species Human Accession NM_000214.2

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone in cloning vector - HG11648-M from Sino Biological Species Human

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11648-CF from Sino Biological Species Human

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11648-NM from Sino Biological Species Human

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11648-NY from Sino Biological Species Human

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11648-CM from Sino Biological Species Human

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone expression plasmid, N-His tag - HG11648-NH from Sino Biological Species Human

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone expression plasmid - HG11648-UT from Sino Biological Species Human

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone expression plasmid, C-His tag - HG11648-CH from Sino Biological Species Human

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11648-CY from Sino Biological Species Human

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11648-ACR from Sino Biological Species Human

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11648-NF from Sino Biological Species Human

Human Jagged 1/JAG1/CD339 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11648-ACG from Sino Biological Species Human

Human JAG1 ORF clone(NM_000214.2) - CDCL185004 from Creative biogene Species Human

Human JAG1 ORF Clone (BC126205) - CDCS405506 from Creative biogene Species Human Accession P78504

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