NFATC3

Gene Symbol NFATC3
Entrez Gene 4775
Alt Symbol NFAT4, NFATX
Species Human
Gene Type protein-coding
Description nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
Other Description NF-ATc3|T cell transcription factor NFAT4|nuclear factor of activated T-cells c3 isoform IE-Xa|nuclear factor of activated T-cells, cytoplasmic 3
Swissprots O75211 Q99840 Q99842 Q14516 Q12968 Q99841
Accessions CAD88555 EAW83210 EAW83211 EAW83212 EAW83213 Q12968 AB209824 BAD93061 AK057574 AK290370 BAF83059 BC001050 AAH01050 BE350846 BU849493 CA418693 DQ895384 ABM86310 EU887605 ACG55625 EU887606 ACG55626 EU887607 ACG55627 EU887608 ACG55628 EU887609 ACG55629 EU887610 ACG55630 EU887611 ACG55631 EU887612 ACG55632 EU887613 ACG55633 EU887614 ACG55634 EU887615 ACG55635 EU887616 ACG55636 EU887617 ACG55637 EU887618 ACG55638 EU887619 ACG55639 EU887620 ACG55640 EU887621 ACG55641 EU887622 ACG55642 EU887623 ACG55643 EU887624 ACG55644 EU887625 ACG55645 L41067 AAA79174 U14510 AAA86308 U85428 AAB46595 U85429 AAB46596 U85430 AAB46597 NM_004555 NP_004546 NM_173163 NP_775186 NM_173165 NP_775188 NM_173164
Function Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2. {ECO:0000269|PubMed:18815128}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18815128}. Nucleus {ECO:0000269|PubMed:18815128}. Note=Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
Tissue Specificity Isoform 1 is predominantly expressed in thymus and is also found in peripheral blood leukocytes and kidney. Isoform 2 is predominantly expressed in skeletal muscle and is also found in thymus, kidney, testis, spleen, prostate, ovary, small intestine, heart, placenta and pancreas. Isoform 3 is expressed in thymus and kidney. Isoform 4 is expressed in thymus and skeletal muscle.
Top Pathways Wnt signaling pathway, HTLV-I infection, MAPK signaling pathway, B cell receptor signaling pathway, T cell receptor signaling pathway

Mouse/Human Phospho-NFAT4 / NFATC3 (Ser165) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1193 from LifeSpan Bioscience

Category ELISA Kit
Prices $550.00
Sizes 1 plate

Mouse/Human NFAT4 / NFATC3 ELISA Kit (Cell-Based ELISA) - LS-F2183 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate

NFAT4 Colorimetric Cell-Based ELISA Kit - CB5486 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

NFAT4 (Phospho-Ser165) Colorimetric Cell-Based ELISA Kit - CBP1184 from Assay Biotechnology

Category ELISA Kit
Prices $480.00, $960.00, $1,440.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3, ELISA Kit - MBS9328190 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

NF-AT Factor, human - DP-10139-X from Nordic BioSite

NFAT4 ELISA Kit - DEIA-XYA1314 from Creative Diagnostics

Category ELISA Kit

NFAT4 (Phospho-Ser165) ELISA Kit - DEIA-XYA1315 from Creative Diagnostics

Category ELISA Kit

Human NFATC3 ELISA Kit - E026903 from Biobool

Category ELISA Kit

Neuronal Nuclear, ELISA Kit - MBS2608339 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear factor of activated T-cells 3, ELISA Kit - MBS2605543 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear factor of activated T-cells 3, ELISA Kit - MBS2604601 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear factor of activated T-cells 3 , ELISA Kit - MBS2607633 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear factor of activated T-cells 3, ELISA Kit - MBS2606496 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear factor of activated T-cells 3, ELISA Kit - MBS2605264 from MyBioSource

Category ELISA Kit
Prices $275.00, $420.00, $1,615.00, $2,880.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear factor of activated T-cells 3, ELISA Kit - MBS2603998 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear factor of activated T-cells 3, ELISA Kit - MBS2605652 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear factor of activated T-cells 3, ELISA Kit - MBS2604503 from MyBioSource

Category ELISA Kit
Prices $290.00, $450.00, $1,755.00, $3,150.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

NFAT4 Colorimetric Cell-Based ELISA Kit - EKA50418 from Biomatik

Category ELISA Kit
Prices $399.00
Sizes 96 tests
Sensitivity At least 5000 cells/well
Range Qualitative
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