Sumo1

Gene Symbol Sumo1
Entrez Gene 22218
Alt Symbol GMP1, PIC1, SENTRIN, SMT3, SMT3H3, SMTP3, SUMO-1, Smt3C, Ubl1
Species Mouse
Gene Type protein-coding
Description SMT3 suppressor of mif two 3 homolog 1 (yeast)
Other Description SMT3 homolog 3|SUMO-1 related peptidase|small ubiquitin-related modifier 1|ubiquitin-homology domain protein PIC1|ubiquitin-like 1|ubiquitin-like protein SMT3C
Swissprots P63166 Q3TX92
Accessions EDL00133 P63166 AF033353 AAC39959 AK002536 BAB22172 AK011074 BAB27379 AK012235 AK089081 BAC40739 AK159366 BAE35024 AK220052 BC082566 AAH82566 BC083158 AAH83158 BE691755 BY242724 NM_009460 NP_033486
Function Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development. {ECO:0000269|PubMed:16990542}.
Subcellular Location Nucleus membrane. Nucleus speckle. Cytoplasm. Nucleus, PML body {ECO:0000250}. Note=Recruited by BCL11A into the nuclear body.
Tissue Specificity Ubiquitous.
Top Pathways RNA transport

Recombinant Small Ubiquitin Related Modifier Protein 1 (SUMO1) - RPG154Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Small ubiquitin-related modifier 1(Sumo1) - CSB-YP022948MO CSB-EP022948MO CSB-BP022948MO CSB-MP022948MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse SUMO1 Protein - SUMO1-16237M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

Small ubiquitin-related modifier 1 (Sumo1), Recombinant Protein - MBS949909 from MyBioSource

Category Protein
Prices $830.00, $830.00, $1,050.00, $1,050.00, $1,185.00, $1,185.00, $1,640.00, $1,640.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse
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