LIMK2

Gene Symbol LIMK2
Entrez Gene 3985
Alt Symbol -
Species Human
Gene Type protein-coding
Description LIM domain kinase 2
Other Description -
Swissprots Q9UFU0 Q96E10 Q7L3H5 Q7KZ80 P53671 A8K6H5 Q99464
Accessions AAB54055 AAB54056 BAA36742 CCQ43329 CCQ43330 EAW59954 EAW59955 EAW59956 EAW59957 EAW59958 EAW59959 P53671 AB451269 BAG70083 AB451396 BAG70210 AK092838 AK093554 BAG52739 AK291640 BAF84329 AK293774 BAG57190 AK299112 BAG61168 AK302553 BAG63822 AK314391 BAG37016 AL117466 CAB55941 AM393090 CAL37968 BC013051 AAH13051 BU553494 BX385507 CR456513 CAG30399 CU013112 CAK54543 CU013400 CAK54842 D45906 BAA08312 D85527 BAA12827 NM_001031801 NP_001026971 NM_005569 NP_005560 NM_016733 NP_057952
Function Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro. {ECO:0000269|PubMed:10436159, ECO:0000269|PubMed:11018042}.
Subcellular Location Isoform LIMK2a: Cytoplasm. Nucleus. Note=Isoform LIMK2a is distributed in the cytoplasm and the nucleus.
Tissue Specificity Highest expression in the placenta; moderate level in liver, lung, kidney, and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver, colon, stomach, and spleen, while in brain, kidney, and placenta LIMK2b is the dominant form. In adult lung, both LIMK2a and LIMK2b is nearly equally observed. {ECO:0000269|PubMed:8954941}.
Top Pathways Axon guidance, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton

LIMK2 (8C11) Rabbit mAb - 3845 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 8C11
Western blot analysis of extracts from Colo201 and Jurkat cells, using LIMK2 (8C11) Rabbit mAb.

LIMK2 Antibody - 3844 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from COS (lane 1), COS transfected with triple HA-tagged LIMK1 (lane 2) and COS transfected with LIMK2 (lane 3), using LIMK2 Antibody.

LIMK-2 (A-12) - sc-365414 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LIMK-2 (A-12): sc-365414. Western blot analysis of LIMK-2 expression in PMA treated THP-1 whole cell lysate.

LIMK-2 (H-78) - sc-5577 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LIMK-2 (H-78): sc-5577. Western blot analysis of LIMK-2 expression in JAR whole cell lysate (A) and mouse placenta extract (B).

LIMK-2 (N-20) - sc-8388 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LIMK-2 (N-20): sc-8388. Immunoperoxidase staining of formalin fixed, paraffin-embedded human colon tissue showing cytoplasmic and membrane staining of glandular cells.

LIMK-2 (R-20) - sc-8390 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LIMK-2 (R-20): sc-8390. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Anti-LIM kinase 2 (phospho S283) antibody - ab111589 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab111589, at a 1/50 dilution, staining LIM kinase in paraffin embedded Human brain tissue by Immunohistochemistry. The image on the right is treated with the synthesized phosphopeptide.

Anti-LIM kinase 2 (phospho S283) antibody - ab195843 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LIM kinase 2 (phospho S283) antibody (ab195843) at 1/500 dilutionLane 1 : NIH 3T3 whole cell lysate with antigen-specific peptideLane 2 : NIH 3T3 whole cell lysateLysates/proteins at 12.5 µg per lane.

Anti-LIM kinase 2 (phospho S291 + S293) antibody - ab76162 from Abcam

Host Sheep
Clonality Polyclonal

Anti-LIM kinase 2 (phospho S291 + S293) antibody - ab76284 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-LIM kinase 2 (phospho T505) antibody - ab38499 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab38499 at a 1:50 dilution staining LIM kinase 2 in Human breast carcinoma tissue using Immunohistochemistry, Paraffin Embedded Tissue. Left image : untreated. Right image : treated with phosphopeptide.

Anti-LIM kinase 2 antibody - ab70116 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab70116 at 1/500 dilution staining LIM kinase 2 in HeLa cells by Immunofluorescence, in the absence or presence of the immunising peptide.

Anti-LIM kinase 2 antibody - ab39659 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LIM kinase 2 antibody (ab39659) at 1/500 dilutionLane 1 : NIH/3T3 with UVLane 2 : A2780 without UV

Anti-LIM kinase 2 antibody - ab196957 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LIM kinase 2 antibody (ab196957) at 1/500 dilutionLane 1 : 3T3 cell extract, treated with PMA (125ng/ml, 30mins)Lane 2 : 3T3 cell extract, treated with PMA (125ng/ml, 30mins) with blocking peptide

Anti-LIM kinase 2 antibody - ab19032 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIM kinase 2 antibody [EP969Y] - ab45165 from Abcam

Prices $368.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP969Y
Anti-LIM kinase 2 antibody [EP969Y] (ab45165) at 1/2000 dilution + Ramos membrane

Anti-LIM kinase 2b antibody - ab93854 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LIM kinase 2b antibody (ab93854) at 1 µg/mlLane 1 : Saos 2 (Human epithelial-like osteosarcoma cell line) Whole Cell LysateLane 2 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lane 3 : Saos 2 (Human epithelial-like osteosarcoma cell line) Whole Cell Lysate with Immunising peptide at 1 µg/mlLane 4 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466) with Immunising peptide at 1 µg/mlLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-LIMK2 Antibody - LS-C342199 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIMK2 Antibody (Lys491) - LS-C176914 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of LIMK2 (K491) pAb in paraffin-embedded human brain tissue.

Anti-LIMK2 Antibody (aa294-655) - LS-C185916 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded CA922 xenograft using LIM kinase 2 antibody at 1:500 dilution.

Anti-LIMK2 Antibody (phospho-Thr505) - LS-C199202 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma, using LIMK2 (Phospho-Thr505) Antibody. The sample on the right was incubated with synthetic peptide.

Anti-LIMK2 Antibody (phospho-Thr505) - LS-C177921 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of p-LIMK2 (T505) pAb in paraffin-embedded human breast carcinoma tissue.

Anti-LIMK2 Antibody (phospho-Thr505) - LS-C34110 from LifeSpan Bioscience

Prices $285.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using LIMK2(Phospho-Thr505) antibody (left) or the same antibody preincubated with blocking peptide (right).

Anti-LIMK2 Antibody - LS-C334045 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using LIMK2 antibody.

Anti-LIMK2 Antibody (clone 2H2-E11) - LS-C197617 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H2-E11
Immunofluorescence of monoclonal antibody to LIMK2 on HeLa cell . [antibody concentration 10 ug/ml]
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