Ptgs1

Gene Symbol Ptgs1
Entrez Gene 19224
Alt Symbol COX1, Cox-1, Cox-3, PGHS-1, PHS 1, Pghs1
Species Mouse
Gene Type protein-coding
Description prostaglandin-endoperoxide synthase 1
Other Description PGH synthase 1|cyclooxygenase-1|prostaglandin G/H synthase 1|prostaglandin H2 synthase 1
Swissprots P22437
Accessions ABA19088 ABA19089 EDL08676 P22437 AK046457 BAC32737 AK134163 BAE22038 AK138432 BAE23660 AK142741 BAE25179 AK159907 BAE35471 AK160886 AK163609 BAE37419 AK167357 BAE39456 AK170414 BAE41780 AK170664 BAE41945 AW493573 AY547265 AAT09993 BC005573 AAH05573 BC023322 AAH23322 CT010314 CAJ18522 HG978383 HG978384 HG978385 M34141 AAA39913 XM_006497790 XP_006497853 XM_006497791 XP_006497854 XM_006497793 XP_006497856 XM_006497794 XP_006497857 XM_006497795 XP_006497858 XM_011239036 XP_011237338 NM_008969 NP_032995
Function Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.
Subcellular Location Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Top Pathways Arachidonic acid metabolism

Cox-1 (H-1) - sc-166573 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cox-1 (H-1): sc-166573. Western blot analysis of Cox-1 expression in NIH/3T3 whole cell lysate.

Cox-1 (M-20) - sc-1754 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of Cox-1 expression in NIH/3T3 (A,C) and KNRK (B) whole cell lysates. Antibodies tested include Cox-1 (C-20): sc-1752 (A,B) and Cox-1 (M-20): sc-1754 (C).

Anti-Cox 1+2 antibody - ab35995 from Abcam

Prices $370.00
Sizes 50 µl
Host Goat
Clonality Polyclonal

Anti-Cox-3 antibody - ab37269 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-COX-3 Antibody (N-Terminus) - LS-C48627 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of COX-3 antibody LS-C48627.

Cox-3 antibody - GTX59716 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-Cox-3 antibody used in Western blot. GTX59716

Anti -Cox-3 (COX1, Cox-1, COX3, PHS 1, Pghs1, PGHS-1) - C7904-73C2 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

COX3 antibody - 70R-12001 from Fitzgerald

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PTGS1 Antibody - abx104041 from Abbexa

Host Rabbit
Clonality Polyclonal

Cyclooxygenase 1 antibody - PAB8657 from Acris Antibodies

Prices $430.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Cyclooxygenase 1 antibody - PAB8658 from Acris Antibodies

Prices $430.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of Ptgs1 expression in mouse small intestine tissue lysate.

Rabbit Anti-Cox-1 Antibody - 168-10264 from RayBiotech

Host Rabbit

Cox-1 Antibody - 3361-100 from Biovision

Prices $245.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Cox-3 Antibody - 3687-100 from Biovision

Prices $245.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Cox-1, Polyclonal Antibody - MBS841330 from MyBioSource

Prices $150.00, $290.00
Sizes 30 µg, 100 µg
Host Rabbit
Clonality Polyclonal

Cox-3, Polyclonal Antibody - MBS840400 from MyBioSource

Prices $150.00, $290.00
Sizes 30 µg, 100 µg
Host Rabbit
Clonality Polyclonal

anti-Cox-3 antibody - ARG20206 from Arigo Biolaboratories

Host Rabbit
Clonality Polyclonal
ARG20206 anti-Cox-3 antibody WB image Western Blot: Mouse small intestine tissue lysate stained with anti-Cox-3 antibody (ARG20206).

Cox-1-Antibody - ABV10264 from Abgent, a WuXi AppTec company

Prices $89.00, $245.00
Sizes 30 µg, 100 µg
Host Rabbit
Clonality Polyclonal

Cox-3-Antibody - ABV10520 from Abgent, a WuXi AppTec company

Prices $89.00, $245.00
Sizes 30 µg, 100 µg
Host Rabbit
Clonality Polyclonal

COX-3 Antibody - AHP2299 from AbD Serotec

Prices $270.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Cyclooxygenase 1 antibody - TA310046 from Acris Antibodies

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of Jurkat cells (Lanes 1 and 2: 62ug cell lysate) with anti-COX1 antibody. (Predicted band size: 70kDa; observed band size: 50kDa)

COX-1 - ARB-62343 from Nordic BioSite

Host Goat
Clone polyclonal

Cox-1 Antibody - 3361 from Biovision

Prices $89.00, $245.00
Sizes 30 µg, 100 µg
Host Rabbit
Clonality Polyclonal

Cox-3 Antibody - 3687 from Biovision

Prices $89.00, $245.00
Sizes 30 µg, 100 µg
Host Rabbit
Clonality Polyclonal

COX-3, Polyclonal Antibody - MBS224881 from MyBioSource

Prices $355.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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