Ptgs1

Gene Symbol	Ptgs1
Entrez Gene	19224
Alt Symbol	COX1, Cox-1, Cox-3, PGHS-1, PHS 1, Pghs1
Species	Mouse
Gene Type	protein-coding
Description	prostaglandin-endoperoxide synthase 1
Other Description	PGH synthase 1|cyclooxygenase-1|prostaglandin G/H synthase 1|prostaglandin H2 synthase 1
Swissprots	P22437
Accessions	ABA19088 ABA19089 EDL08676 P22437 AK046457 BAC32737 AK134163 BAE22038 AK138432 BAE23660 AK142741 BAE25179 AK159907 BAE35471 AK160886 AK163609 BAE37419 AK167357 BAE39456 AK170414 BAE41780 AK170664 BAE41945 AW493573 AY547265 AAT09993 BC005573 AAH05573 BC023322 AAH23322 CT010314 CAJ18522 HG978383 HG978384 HG978385 M34141 AAA39913 XM_006497790 XP_006497853 XM_006497791 XP_006497854 XM_006497793 XP_006497856 XM_006497794 XP_006497857 XM_006497795 XP_006497858 XM_011239036 XP_011237338 NM_008969 NP_032995
Function	Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.
Subcellular Location	Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Top Pathways	Arachidonic acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse PTGS1 Protein - abx068703 from Abbexa Category Protein Source E.coli Species Mouse

Prostaglandin Endoperoxide Synthase 1 (PTGS1), Mouse - 20-7044 from ARP American Research Products Category Protein Prices $583.00 Sizes 50 µg Source E.coli Species Mouse

Recombinant Mouse Prostaglandin G/H synthase 1(Ptgs1) - CSB-YP018985MO CSB-EP018985MO CSB-BP018985MO CSB-MP018985MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Prostaglandin Endoperoxide Synthase 1 (PTGS1), Recombinant Protein - MBS2011942 from MyBioSource Category Protein Prices $205.00, $455.00, $710.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

Prostaglandin G/H synthase 1 (Ptgs1), Recombinant Protein - MBS965395 from MyBioSource Category Protein Prices $1,375.00, $1,375.00, $1,595.00, $1,595.00, $2,290.00, $2,290.00, $2,755.00, $2,755.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

Cox-1, Peptide - MBS843553 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

Recombinant Mouse PTGS1 Protein - PTGS1-13650M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

PTGS1 Recombinant Protein (OPCD06481) - OPCD06481 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

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