DUT

Gene Symbol	DUT
Entrez Gene	1854
Alt Symbol	dUTPase
Species	Human
Gene Type	protein-coding
Description	deoxyuridine triphosphatase
Other Description	dUTP diphosphatase|dUTP nucleotidohydrolase|dUTP pyrophosphatase|deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Swissprots	Q6NSA3 Q16860 Q16708 Q6FHN1 A8K650 P33316 B4DPR5 O14785 Q96Q81
Accessions	AAB71393 AAB71394 AAB93866 AAB93867 AAX14045 EAW77349 EAW77350 EAW77351 EAW77352 P33316 AB049113 BAB13724 AK000629 AK291515 BAF84204 AK298464 BAG60677 AK312122 BAG35058 BC033645 AAH33645 BC070339 AAH70339 BC110377 AAI10378 BF697257 BG505144 BG532018 BI257870 CR541720 CAG46521 CR541781 CAG46580 DQ891191 ABM82117 DQ894375 ABM85301 L11877 AAA36801 M89913 AAA58444 U31930 AAC50418 U62891 AAC51123 U90223 AAB94642 XM_011521315 XP_011519617 XR_931760 NM_001025248 NP_001020419 NM_001025249 NP_001020420 NM_001948 NP_001939
Function	This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. {ECO:0000269|PubMed:8805593}.
Subcellular Location	Isoform 2: Nucleus.
Tissue Specificity	Found in a variety of tissues. Isoform 3 expression is constitutive, while isoform 2 expression correlates with the onset of DNA replication (at protein level). Isoform 2 degradation coincides with the cessation of nuclear DNA replication (at protein level). {ECO:0000269|PubMed:9228092}.
Top Pathways	Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active DUT full length protein - ab68279 from Abcam Category Protein Prices $432.00 Sizes 500 units Source E. coli

Human DUT full length protein - ab99388 from Abcam Category Protein Source E. coli Species Human

Human DUT full length protein - ab173062 from Abcam Category Protein Source E. coli Species Human

DUT / DUTPase Antibody Blocking Peptide - LS-E3066 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DUT / DUTPase Antibody Blocking Peptide - LS-E16767 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

dUTPase Partial Recombinant Protein - H00001854-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

dUTPase Partial Recombinant Protein - H00001854-Q02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

dUTPase Recombinant Protein - H00001854-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human dUTPase Protein - NBP1-48598 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

DUT-Antibody-C-term-Blocking-Peptide - BP14203b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DUT Protein Lysate (APL10341) - APL10341 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

DUT Protein (OPPA02550) - OPPA02550 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human DUT protein - orb168257 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human Dutpase protein - orb163472 from Biorbyt Category Protein Prices $289.00, $621.00, $2,321.00, $3,281.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

DUT Blocking Peptide - 33R-6682 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DUT Blocking Peptide - 33R-1060 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DUT protein (His tag) - 80R-1487 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

DUT (70-252, His-tag) - AR09663PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

DUT (70-252, His-tag) - AR09663PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

DUT - H00001854-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

DUT - H00001854-P01-25 from Acris Antibodies Category Protein Prices $460.00 Sizes 25 µg Species Human

DUT (mitochondrial) - H00001854-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DUT (mitochondrial) - H00001854-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DUT - H00001854-Q02 from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Species Human

DUT - H00001854-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

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