PRDX1

Gene Symbol	PRDX1
Entrez Gene	5052
Alt Symbol	MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2
Species	Human
Gene Type	protein-coding
Description	peroxiredoxin 1
Other Description	natural killer cell-enhancing factor A|natural killer-enhancing factor A|peroxiredoxin-1|proliferation-associated gene A|proliferation-associated gene protein|thioredoxin peroxidase 2|thioredoxin-dependent peroxide reductase 2
Swissprots	Q5T155 Q2V576 B5BU26 Q06830 D3DPZ8 P35703 Q5T154
Accessions	ABB84465 CAH59516 EAX06975 EAX06976 EAX06977 EAX06978 EAX06979 EAX06980 EAX06981 EAX06982 Q06830 AB451262 BAG70076 AB451388 BAG70202 AI912389 AK131049 AK311898 BAG34839 AV691526 BC007063 AAH07063 BC021683 AAH21683 BM740381 BM762399 BM787105 BM827394 BT019740 AAV38545 BU564066 CD638470 CR407652 CAG28580 DQ893173 ABM84099 DQ896472 ABM87471 L19184 AAA50464 X67951 CAA48137 NM_001202431 NP_001189360 NM_002574 NP_002565 NM_181696 NP_859047 NM_181697 NP_859048
Function	Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Peroxisome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PRDX1-Over-expression-Lysate - LY10783a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

PRDX1 overexpression lysate - LY403646 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PRDX1 overexpression lysate - LY419239 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PRDX1 293 Cell Lysate - 409015 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PRDX1 293 Cell Lysate - 403143 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Peroxiredoxin 1 Overexpression Lysate (Native) - NBL1-14737 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Peroxiredoxin 1 Overexpression Lysate (Native) - NBL1-14738 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PRDX1 Over-expression Lysate Product - GWB-FD367F from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

PRDX1 Over-expression Lysate Product - GWB-B1FCF0 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Peroxiredoxin 1 Overexpression Lysate (Native) - NBP2-04806 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human PRDX1 Knockdown Stable Cell Line - CSC-DC012359 from Creative biogene Category Cell Line Species Human

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