VDR

Gene Symbol VDR
Entrez Gene 7421
Alt Symbol NR1I1, PPP1R163
Species Human
Gene Type protein-coding
Description vitamin D (1,25- dihydroxyvitamin D3) receptor
Other Description 1,25-dihydroxyvitamin D3 receptor|nuclear receptor subfamily 1 group I member 1|protein phosphatase 1, regulatory subunit 163|vitamin D nuclear receptor variant 1|vitamin D3 receptor
Swissprots G3V1V9 P11473 B2R5Q1 Q5PSV3
Accessions AAP88938 AAR10771 AAR19315 AAR19316 AAV85448 AGU41796 AGU41797 AGU41798 AGU41799 AGU41800 AGU41801 AGU41802 AGU41803 AGU41804 AGU41805 AGU41806 AGU41807 AGU41808 AGU41809 AGU41810 AGU41811 AID81985 BAA83389 CAC42552 EAW57959 EAW57960 EAW57961 EAW57962 EAW57963 P11473 AB307700 BAH02291 AF026260 AAB95155 AK024830 AK225844 AK299446 BAG61419 AK312267 BAG35198 BC033465 BC060832 AAH60832 BM685276 BM908433 BQ002808 BX355584 CF138099 DA721726 EU446665 ABZ92194 EU831779 ACE87297 EU831857 ACE86616 HQ692836 ADZ17347 J03258 AAA61273 M65208 AAA61274 X67482 CAA47824 XM_006719587 XP_006719650 XM_011538720 XP_011537022 NM_000376 NP_000367 NM_001017535 NP_001017535 NM_001017536 NP_001017536
Function Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. {ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:15728261, ECO:0000269|PubMed:16252006, ECO:0000269|PubMed:16913708}.
Subcellular Location Nucleus.
Top Pathways Mineral absorption, Endocrine and other factor-regulated calcium reabsorption, Tuberculosis

Vitamin D3 Receptor (D2K6W) Rabbit mAb - 12550 from Cell Signaling Technology

Prices $250.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2K6W
Western blot analysis of extracts from various cell lines using Vitamin D3 Receptor (D2K6W) Rabbit mAb.

VDR (C-20) - sc-1008 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VDR (C-20): sc-1008. Western blot analysis of VDR expression in KNRK whole cell lysate.

VDR (D-6) - sc-13133 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VDR (D-6) sc-13133. Immunoperoxidase staining of formalin fixed, paraffin-embedded human adrenal gland tissue showing nuclear staining of cortical cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

VDR (H-81) - sc-9164 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VDR (H-81): sc-9164. Western blot analysis of VDR expression in SK-BR-3 whole cell lysate.

VDR (N-20) - sc-1009 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VDR (N-20): sc-1009. Western blot analysis of VDR expression in non-transfected: sc-117752 (A) and mouse VDR transfected: sc-124548 (B) 293T whole cell lysates.

Anti-Vitamin D Receptor (phospho S208) antibody - ab195917 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Vitamin D Receptor (phospho S208) antibody (ab195917) at 1/500 dilutionLane 1 : Heatshock treated HT29 whole cell lysates with antigen-specific peptideLane 2 : Heatshock treated HT29 whole cell lysatesLysates/proteins at 12.5 µg per lane.

Anti-Vitamin D Receptor antibody - ab137371 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Vitamin D Receptor antibody (ab137371) at 1/1000 dilutionLane 1 : H1299 whole cell lysateLane 2 : HeLa whole cell lysateLane 3 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Vitamin D Receptor antibody [2F4] - ab110106 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2F4
Immunohistochemistry Image of Human Breast: Formalin-Fixed, Paraffin-Embedded tissue using ab110106 at 5 µg/ml.

Anti-Vitamin D Receptor antibody [333C6a] - ab54373 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 333C6a
Anti-Vitamin D Receptor antibody [333C6a] (ab54373) + immunised recombinant protein

Anti-Vitamin D Receptor antibody [9A7] - ab8756 from Abcam

Prices $394.00
Sizes 500 µl
Host Rat
Clonality Monoclonal
Clone 9A7
Anti-Vitamin D Receptor antibody [9A7] (ab8756) at 1/1000 dilution + Whole cell lysate prepared from chinese hamster CHO cells at 50000 cellsSecondaryHRP conjugated goat polyclonal to rat Ig at 1/1000 dilutionPerformed under reducing conditions.

Anti-Vitamin D Receptor antibody [9A7 gamma .E10.E4] - ab80666 from Abcam

Prices $372.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 9A7 gamma .E10.E4

Anti-Vitamin D Receptor antibody [9A7gammaE10.4] - ab54387 from Abcam

Prices $359.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 9A7gammaE10.4

Anti-Vitamin D Receptor antibody [EPR4552] - ab109234 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4552
All lanes : Anti-Vitamin D Receptor antibody [EPR4552] (ab109234) at 1/1000 dilution (unpurified)Lane 1 : T47D cell lysateLane 2 : SKBR-3 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP-conjugated goat anti-rabbit IgG at 1/2000 dilution

Anti-Vitamin D Receptor antibody - ChIP Grade - ab3508 from Abcam

Prices $401.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Ab3508 staining Human normal jejunum. Staining is localized to the nucleus.Left panel: with primary antibody at 1/2000. Right panel: isotype control.Sections were stained using an automated system DAKO Autostainer Plus , at room temperature. Sections were rehydrated and antigen retrieved with the Dako 3-in-1 AR buffer, citrate pH 6.0 in a DAKO PT Link. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 minutes. They were then blocked with Dako Protein block for 10 minutes (containing casein 0.25% in PBS) then incubated with primary antibody for 20 minutes and detected with Dako Envision Flex amplification kit for 30 minutes. Colorimetric detection was completed with Diaminobenzidine for 5 minutes. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that for manual staining we recommend to optimize the primary antibody concentration and incubation time (overnight incubation), and amplification may be required.

Anti-Vitamin D Receptor (phospho S208) antibody - ab63572 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescent staining of A549 cells, using ab63572 at a 1/500 dilution, minus immunising peptide (left image) and plus immunising peptide (right image).

Anti-Vitamin D Receptor (phospho S51) antibody - ab79311 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Vitamin D Receptor (phospho S51) antibody (ab79311) at 1/500 dilutionLane 1 : COLO cells extract treated with insulin (0.01U/ml, 15mins)Lane 2 : COLO cells extract treated with insulin (0.01U/ml, 15mins) with Immunizing phosphopeptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-Vitamin D Receptor antibody - ab115495 from Abcam

Prices $376.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
ab115495, at 10 &microg/ml, staining Vitamin D Receptor in formalin-fixed, paraffin-embedded Human Colon tissue by Immunohistochemistry using a biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Vitamin D Receptor antibody - ab134826 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of HeLa cells labelling Vitamin D Receptor with ab134826 at 1/100 dilution. The image on the right is treated with the synthesized peptide.

Anti-Vitamin D Receptor antibody - ab82566 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Vitamin D Receptor antibody (ab82566) at 1 µg/mlLane 1 : Skin (Human) Tissue Lysate - adult normal tissue (ab30166)Lane 2 : Thyroid (Human) Whole Cell Lysate - adult normal tissue (ab29636)Lane 3 : Small Intestine (Human) Tissue Lysate - adult normal tissue (ab29276)Lane 4 : Bone Marrow (Human) Tissue Lysate - adult normal tissueLane 5 : Kidney (Human) Tissue Lysate - adult normal tissue (ab30203)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Vitamin D Receptor antibody - ab79513 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Vitamin D Receptor antibody (ab79513) at 1/500 dilutionLane 1 : Extracts from Jurkat cellsLane 2 : Extracts from Jurkat cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Vitamin D Receptor antibody - ab61781 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of HeLa cells, using ab61781 antibody at 1/500 dilution in the presence and absence of the immunizing peptide

Anti-Vitamin D Receptor antibody - ab89626 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Vitamin D Receptor antibody (ab89626) at 1 µg/ml + 293 Cell lysate at 50 µg

Anti-Vitamin D Receptor antibody - ab39990 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Vitamin D Receptor antibody (ab39990) at 0.3 µg/ml (for 1 hour) + Human Brain lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-Vitamin D Receptor antibody - ab131012 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Detection of Vitamin D Receptor by Western Blot of Immunprecipitate. Anti-Vitamin D Receptor antibody at 1µg/ml staining Vitamin D Receptor in HeLa whole cell lysate immunoprecipitated using ab131012 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 3 minutes.

Anti-Vitamin D Receptor / VDR Antibody (clone 9A7gamma.E10.E4, Azide-free) - LS-C88859 from LifeSpan Bioscience

Prices $620.00, $990.00
Sizes 100 µg, 200 µg
Host Rat
Clonality Monoclonal
Clone 9A7gamma.E10.E4
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