VDR

Gene Symbol	VDR
Entrez Gene	7421
Alt Symbol	NR1I1, PPP1R163
Species	Human
Gene Type	protein-coding
Description	vitamin D (1,25- dihydroxyvitamin D3) receptor
Other Description	1,25-dihydroxyvitamin D3 receptor|nuclear receptor subfamily 1 group I member 1|protein phosphatase 1, regulatory subunit 163|vitamin D nuclear receptor variant 1|vitamin D3 receptor
Swissprots	G3V1V9 P11473 B2R5Q1 Q5PSV3
Accessions	AAP88938 AAR10771 AAR19315 AAR19316 AAV85448 AGU41796 AGU41797 AGU41798 AGU41799 AGU41800 AGU41801 AGU41802 AGU41803 AGU41804 AGU41805 AGU41806 AGU41807 AGU41808 AGU41809 AGU41810 AGU41811 AID81985 BAA83389 CAC42552 EAW57959 EAW57960 EAW57961 EAW57962 EAW57963 P11473 AB307700 BAH02291 AF026260 AAB95155 AK024830 AK225844 AK299446 BAG61419 AK312267 BAG35198 BC033465 BC060832 AAH60832 BM685276 BM908433 BQ002808 BX355584 CF138099 DA721726 EU446665 ABZ92194 EU831779 ACE87297 EU831857 ACE86616 HQ692836 ADZ17347 J03258 AAA61273 M65208 AAA61274 X67482 CAA47824 XM_006719587 XP_006719650 XM_011538720 XP_011537022 NM_000376 NP_000367 NM_001017535 NP_001017535 NM_001017536 NP_001017536
Function	Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. {ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:15728261, ECO:0000269|PubMed:16252006, ECO:0000269|PubMed:16913708}.
Subcellular Location	Nucleus.
Top Pathways	Mineral absorption, Endocrine and other factor-regulated calcium reabsorption, Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® Vitamin D3 Receptor siRNA I - 12719 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Human

VDR CRISPR/Cas9 KO Plasmid (h) - sc-400171 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

VDR HDR Plasmid (h) - sc-400171-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

VDR Double Nickase Plasmid (h) - sc-400171-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

VDR Double Nickase Plasmid (h2) - sc-400171-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

VDR CRISPR Activation Plasmid (h) - sc-400171-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

VDR CRISPR Activation Plasmid (h2) - sc-400171-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

VDR Lentiviral Activation Particles (h) - sc-400171-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

VDR Lentiviral Activation Particles (h2) - sc-400171-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

VDR siRNA (h2) - sc-45920 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

VDR shRNA Plasmid (h2) - sc-45920-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

VDR shRNA (h2) Lentiviral Particles - sc-45920-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

VDR siRNA (h) - sc-106692 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

VDR shRNA Plasmid (h) - sc-106692-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

VDR shRNA (h) Lentiviral Particles - sc-106692-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

VDR/NR1I1/Vitamin D Receptor RNAi - H00007421-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

VDR/NR1I1/Vitamin D Receptor RNAi - H00007421-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU010441 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1868 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1868 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

VDR siRNA (Human) - CRH5077 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

VDR - MBS8232992 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human VDR (NM_000376.2) - SHH442548 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human VDR(NM_000376.2) - SHL122624 from Creative biogene Category siRNA Species Reactivities Human

Human VDR siRNA - orb265579 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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