CFB

Gene Symbol	CFB
Entrez Gene	629
Alt Symbol	AHUS4, ARMD14, BF, BFD, CFAB, CFBD, FB, FBI12, GBG, H2-Bf, PBF2
Species	Human
Gene Type	protein-coding
Description	complement factor B
Other Description	B-factor, properdin|C3 proaccelerator|C3 proactivator|C3/C5 convertase|glycine-rich beta glycoprotein|glycine-rich beta-glycoprotein|properdin factor B
Swissprots	Q5JP67 Q53F89 Q5ST50 O15006 P00751 Q9BX92 Q96HX6 Q9BTF5 B0QZQ6 Q29944
Accessions	AAA59625 AAB67977 AAN71991 AAQ13379 AAQ13380 AAQ13401 EAX03550 P00751 AF349679 AAK30167 AK130533 AK223400 BAD97120 AK304042 BAG64953 AL701961 BC004143 AAH04143 BC007990 AAH07990 BI258352 CD689714 DC368322 DQ892313 ABM83239 DQ895516 ABM86442 J00126 AAA36226 J00185 AAA36219 J00186 AAA36220 K01566 AAA36225 L15702 AAA16820 S67310 AAD13989 X00284 CAA25077 X72875 CAA51389 NM_001710 NP_001701
Function	Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Staphylococcus aureus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Complement factor B protein fragment - ab174401 from Abcam Category Protein Source E. coli Species Human

Human Factor B full length protein - ab151392 from Abcam Category Protein Source HEK 293 cells Species Human

Human Factor B protein fragment - ab73657 from Abcam Category Protein Source EBNA 293 cell line Species Human

Human Factor B protein fragment - ab177660 from Abcam Category Protein Source E. coli Species Human

CFB / Complement Factor B Antibody Blocking Peptide - LS-E8889 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CFB / Complement Factor B Antibody Blocking Peptide - LS-E9908 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Complement Factor B Protein - NBP2-22796 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

BF-Antibody-Center-Blocking-Peptide - BP7357c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CFB-Antibody-Center-Blocking-Peptide - BP9036c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Mouse Cfb protein - orb244106 from Biorbyt Category Protein Prices $213.00, $408.00, $612.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg Species Mouse

Human CFB protein - orb244105 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human Complement Factor B protein - orb49307 from Biorbyt Category Protein Prices $323.00, $485.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

CFB protein (His tag) - 80R-3674 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

CFBBb protein (His tag) - 80R-3612 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

Complement Factor B - 30C-CP2036U from Fitzgerald Prices $370.80 Sizes 250 µg

Human Complement Factor B Protein - abx066066 from Abbexa Category Protein Source E.coli Species Human

Human Complement Factor B Protein - abx066069 from Abbexa Category Protein Source E.coli Species Human

Human Complement Factor B Protein - abx066073 from Abbexa Category Protein Source E.coli Species Human

Complement factor B (260-764, His-tag) - AR51299PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Complement factor B (260-764, His-tag) - AR51299PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Complement factor B (His-tag) - AR51361PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Complement factor B (His-tag) - AR51361PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Complement factor B - P5887 from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Species Human

Complement factor B - P5888 from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Species Human

CFB, 26- 259aa, Human, His tag, E.coli - 01-P2541 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

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