CFB

Gene Symbol CFB
Entrez Gene 629
Alt Symbol AHUS4, ARMD14, BF, BFD, CFAB, CFBD, FB, FBI12, GBG, H2-Bf, PBF2
Species Human
Gene Type protein-coding
Description complement factor B
Other Description B-factor, properdin|C3 proaccelerator|C3 proactivator|C3/C5 convertase|glycine-rich beta glycoprotein|glycine-rich beta-glycoprotein|properdin factor B
Swissprots Q5JP67 Q53F89 Q5ST50 O15006 P00751 Q9BX92 Q96HX6 Q9BTF5 B0QZQ6 Q29944
Accessions AAA59625 AAB67977 AAN71991 AAQ13379 AAQ13380 AAQ13401 EAX03550 P00751 AF349679 AAK30167 AK130533 AK223400 BAD97120 AK304042 BAG64953 AL701961 BC004143 AAH04143 BC007990 AAH07990 BI258352 CD689714 DC368322 DQ892313 ABM83239 DQ895516 ABM86442 J00126 AAA36226 J00185 AAA36219 J00186 AAA36220 K01566 AAA36225 L15702 AAA16820 S67310 AAD13989 X00284 CAA25077 X72875 CAA51389 NM_001710 NP_001701
Function Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Subcellular Location Secreted.
Top Pathways Complement and coagulation cascades, Staphylococcus aureus infection

Factor B CRISPR/Cas9 KO Plasmid (h) - sc-402091 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor B HDR Plasmid (h) - sc-402091-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor B Double Nickase Plasmid (h) - sc-402091-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor B Double Nickase Plasmid (h2) - sc-402091-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor B CRISPR Activation Plasmid (h) - sc-402091-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor B CRISPR Activation Plasmid (h2) - sc-402091-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor B Lentiviral Activation Particles (h) - sc-402091-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor B Lentiviral Activation Particles (h2) - sc-402091-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor B siRNA (h) - sc-44510 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Factor B shRNA Plasmid (h) - sc-44510-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Factor B shRNA (h) Lentiviral Particles - sc-44510-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU105341 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5994 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5994 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CFB siRNA (Human) - CRH0426 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CFB - MBS828328 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CFB (NM_001710.5) - SHH262365 from Creative biogene

Category siRNA
Species Reactivities Human

CFB shRNA Plasmid (Human) - CHH0426 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CFB miRNA 3'UTR clone - MiUTR3H-00925 from Creative biogene

Species Reactivities Human
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