| Gene Symbol |
Hras
|
| Entrez Gene |
293621
|
| Alt Symbol |
HRAS1, c-H-ras
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
Harvey rat sarcoma virus oncogene
|
| Other Description |
GTPase HRas|H-Ras-1|Harvey ras1 protein|Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog|p21ras|transforming protein p21
|
| Swissprots |
Q4KLL6 P20171 Q5RJJ8
|
| Accessions |
AAA42009 AAN76327 EDM11987 EDM11988 P20171 BC086608 AAH86608 BC099130 AAH99130 CO567790 XM_006230535 XP_006230597 NM_001098241 NP_001091711 NM_001130441 NP_001123913
|
| Function |
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:19878719}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Note=Shuttles between the plasma membrane and the Golgi apparatus (By similarity). The active GTP-bound form is localized most strongly to membranes than the inactive GDP-bound form. {ECO:0000250}.
|
| Top Pathways |
Axon guidance, Estrogen signaling pathway, Viral carcinogenesis, Sphingolipid signaling pathway, Proteoglycans in cancer
|