| Gene Symbol | Hras |
|---|---|
| Entrez Gene | 293621 |
| Alt Symbol | HRAS1, c-H-ras |
| Species | Rat |
| Gene Type | protein-coding |
| Description | Harvey rat sarcoma virus oncogene |
| Other Description | GTPase HRas|H-Ras-1|Harvey ras1 protein|Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog|p21ras|transforming protein p21 |
| Swissprots | Q4KLL6 P20171 Q5RJJ8 |
| Accessions | AAA42009 AAN76327 EDM11987 EDM11988 P20171 BC086608 AAH86608 BC099130 AAH99130 CO567790 XM_006230535 XP_006230597 NM_001098241 NP_001091711 NM_001130441 NP_001123913 |
| Function | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:19878719}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Note=Shuttles between the plasma membrane and the Golgi apparatus (By similarity). The active GTP-bound form is localized most strongly to membranes than the inactive GDP-bound form. {ECO:0000250}. |
| Top Pathways | Axon guidance, Estrogen signaling pathway, Viral carcinogenesis, Sphingolipid signaling pathway, Proteoglycans in cancer |
CompoZr® Knockout ZFN Kit - CKOZFN55181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND55181 from Sigma-Aldrich
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HRAS siRNA (Rat) - CRR4292 from Cohesion Biosciences
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HRAS - MBS8228060 from MyBioSource
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shRNA set against Rat HRAS (NM_001098241.1) - SHH314777 from Creative biogene
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Rat HRAS siRNA - orb299141 from Biorbyt
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HRAS shRNA Plasmid (Rat) - CHR4292 from Cohesion Biosciences
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