LTA4H

Gene Symbol LTA4H
Entrez Gene 4048
Alt Symbol -
Species Human
Gene Type protein-coding
Description leukotriene A4 hydrolase
Other Description LTA-4 hydrolase|leukotriene A-4 hydrolase
Swissprots B4DNQ9 F8VV40 Q6IAT6 P09960 Q9UCT7
Accessions AAA89077 AAC24315 EAW97557 EAW97558 EAW97559 EAW97560 P09960 AB209740 BAD92977 AK293630 BAG57086 AK298017 BAG60321 AK301308 BAG62860 AK308184 AK310461 AK310522 BC032528 AAH32528 BC036555 AAH36555 BX647158 CR457068 CAG33349 DB019628 DC358373 J02959 AAA36177 J03459 AAA36176 JF432734 ADZ15951 R41544 XM_005268871 XP_005268928 XM_011538348 XP_011536650 XM_011538349 XP_011536651 NM_000895 NP_000886 NM_001256643 NP_001243572 NM_001256644 NP_001243573
Function Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. {ECO:0000269|PubMed:11917124, ECO:0000269|PubMed:12207002, ECO:0000269|PubMed:15078870, ECO:0000269|PubMed:18804029, ECO:0000269|PubMed:1897988, ECO:0000269|PubMed:1975494, ECO:0000269|PubMed:2244921}.
Subcellular Location Cytoplasm.
Tissue Specificity Isoform 1 and isoform 2 are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts.
Top Pathways Arachidonic acid metabolism

LTA4H CRISPR/Cas9 KO Plasmid (h) - sc-404695 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTA4H HDR Plasmid (h) - sc-404695-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTA4H Double Nickase Plasmid (h) - sc-404695-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTA4H Double Nickase Plasmid (h2) - sc-404695-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTA4H CRISPR Activation Plasmid (h) - sc-404695-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTA4H CRISPR Activation Plasmid (h2) - sc-404695-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTA4H Lentiviral Activation Particles (h) - sc-404695-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTA4H Lentiviral Activation Particles (h2) - sc-404695-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTA4H siRNA (h) - sc-43895 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LTA4H shRNA Plasmid (h) - sc-43895-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LTA4H shRNA (h) Lentiviral Particles - sc-43895-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Leukotriene A4 Hydrolase/LTA4H RNAi - H00004048-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU156201 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12811 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12811 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02337 from Sigma-Aldrich

Category miRNA

LTA4H siRNA (Human) - CRH2737 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LTA4H (NM_000895.2) - SHH335411 from Creative biogene

Category siRNA
Species Reactivities Human

LTA4H shRNA Plasmid (Human) - CHH2737 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LTA4H miRNA 3'UTR clone - MiUTR3H-01319 from Creative biogene

Species Reactivities Human
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