PDHA1

Gene Symbol	PDHA1
Entrez Gene	5160
Alt Symbol	PDHA, PDHAD, PDHCE1A, PHE1A
Species	Human
Gene Type	protein-coding
Description	pyruvate dehydrogenase (lipoamide) alpha 1
Other Description	PDHE1-A type I|pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial|pyruvate dehydrogenase complex, E1-alpha polypeptide 1
Swissprots	Q53H41 B7Z3T7 A5YVE9 Q9NP12 Q9UBJ8 Q5JPT8 Q9UNG5 Q9UBU0 P08559 Q9UNG4 B7Z3X5 B2R5P7
Accessions	AAA31853 AAA60051 AAB32351 AAB39723 AAB39724 AAB39725 AAB39726 AAB39727 AAB39728 AAB39729 AAB39730 AAD16047 AAD23841 AAD23842 AAD23843 AAD23844 AAD23845 AAD23846 AAD23847 AAD23848 AAD23849 AAD23850 AAD23851 AAD23852 AAD23853 AAD23854 AAD23855 AAD23856 AAD23857 AAD23858 AAD23859 AAD23860 AAD23861 AAD23862 AAD23863 AAD23864 AAD23866 AAD23867 AAD23868 AAD23869 AAD23870 AAD23871 AAD23872 AAD23873 AAD23874 AAD23875 AAD23876 BAA14121 EAW98960 EAW98961 P08559 AK129887 AK222740 BAD96460 AK222988 BAD96708 AK293250 BAH11476 AK296341 BAH12323 AK296457 BAH12361 AK312263 BAG35194 AW204705 BC002406 AAH02406 BU170389 DA075402 DC361191 DQ891865 ABM82791 DQ895054 ABM85980 DQ895057 ABM85983 EF576990 ABQ58815 EF590116 EF590117 ABQ59099 J03503 AAA60055 J03575 AAA60050 L13318 AAA60227 L48690 AAB59581 M24848 AAA36533 R49470 S89908 AAB21863 X52709 CAA36933 X52710 CAA36934 XM_011545531 XP_011543833 XM_011545532 XP_011543834 NM_000284 NP_000275 NM_001173454 NP_001166925 NM_001173455 NP_001166926 NM_001173456 NP_001166927
Function	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. {ECO:0000269|PubMed:19081061, ECO:0000269|PubMed:7782287}.
Subcellular Location	Mitochondrion matrix.
Tissue Specificity	Ubiquitous.
Top Pathways	Glycolysis / Gluconeogenesis, Citrate cycle (TCA cycle), Central carbon metabolism in cancer, Glucagon signaling pathway, Pyruvate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Pyruvate Dehydrogenase E1-alpha subunit full length protein - ab125602 from Abcam Category Protein Source E. coli Species Human

Human Pyruvate Dehydrogenase E1-alpha subunit full length protein - ab91940 from Abcam Category Protein Source E. coli Species Human

Human Pyruvate Dehydrogenase E1-alpha subunit peptide - ab103930 from Abcam Category Peptide

Pyruvate Dehydrogenase E1-alpha subunit peptide - ab170730 from Abcam Category Peptide

PDHA1 / PDH E1 Alpha Antibody Blocking Peptide - LS-E7885 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDHA1 / PDH E1 Alpha Antibody Blocking Peptide - LS-E10246 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Pyruvate Dehydrogenase E1-alpha subunit Protein - H00005160-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

BDHA1-Antibody-Center-Blocking-peptide - BP5553c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PDHA1-Antibody-Center-Blocking-Peptide - BP9652c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human PDHA1 protein (GST Tag) - orb139465 from Biorbyt Category Protein Prices $417.00, $859.00 Sizes 20 μg, 100 μg Source Baculovirus-Insect Cells Species Human

Human PDHA1 protein - orb139464 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Baculovirus-Insect Cells Species Human

PDHA1 Blocking Peptide - 33R-4304 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PDHA1 Blocking Peptide - 33R-6366 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human PDHa Protein - abx068801 from Abbexa Category Protein Source E.coli Species Human

PDHA1 - H00005160-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PDHA1 - H00005160-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Pyruvate Dehydrogenase Alpha (PDHa), Human - 20-7087 from ARP American Research Products Category Protein Prices $511.00 Sizes 50 µg Source E.coli Species Human

PDHA1 fusion protein - Ag12556 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

PDHA1 fusion protein - ag12701 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human PDHA1 protein, His-tagged - PDHA1-28668TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human PDHA1, His-GST tagged - PDHA1-245H from Creative Biomart Category Protein Source Baculovirus-Insect cells Species Human

Recombinant Human PDHA1, Gly & Pro tagged - PDHA1-266H from Creative Biomart Category Protein Source Baculovirus-Insect cells Species Human

Recombinant Human PDHA1, His-tagged - PDHA1-1613H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Pyruvate Dehydrogenase Alpha (PDHa) - RPA776Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Pyruvate Dehydrogenase Alpha (PDHa) - RPA776Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

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