HMGB1

Gene Symbol	HMGB1
Entrez Gene	3146
Alt Symbol	HMG1, HMG3, SBP-1
Species	Human
Gene Type	protein-coding
Description	high mobility group box 1
Other Description	Amphoterin|HMG-1|Sulfoglucuronyl carbohydrate binding protein|high mobility group protein 1|high mobility group protein B1|high-mobility group (nonhistone chromosomal) protein 1|high-mobility group box 1
Swissprots	Q14321 A5D8W9 P09429 Q6IBE1 Q5T7C3
Accessions	AAB08987 AAF71287 AAK64599 ABM47301 ABS29271 EAX08457 EAX08458 EAX08459 EAX08460 EAX08461 EAX08462 P09429 AA430980 AB208998 BAD92235 AF401215 AK057120 BAG51867 AK122825 BAG53745 AK291494 BAF84183 AK304506 BAH14201 AK310975 AL110194 AX795278 CAE48262 AY377859 AAQ91389 BC003378 AAH03378 BC030981 AAH30981 BC066889 AAH66889 BC067732 AAH67732 BC140013 AAI40014 BC140018 AAI40019 BC141844 AAI41845 BT006940 AAP35586 BT020159 AAV38961 BX647267 CR456863 CAG33144 CR749614 CAH18408 D63874 BAA09924 L13804 L13805 X12597 CAA31110 XM_005266363 XP_005266420 XM_005266365 XP_005266422 XM_005266368 XP_005266425 XM_011535055 XP_011533357 XM_011535056 XP_011533358 XR_941568 NM_002128 NP_002119
Function	DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus. Chromosome.
Top Pathways	Base excision repair

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human HMGB1 full length protein - ab167718 from Abcam Category Protein Prices $465.00 Sizes 100 µg Source HEK 293 cells Species Human

Active mouse HMGB1 full length protein - ab181949 from Abcam Category Protein Prices $1,592.00 Sizes 100 µg Source E. coli Species Mouse

Cow HMGB1 full length protein - ab82100 from Abcam Category Protein Prices $450.00 Sizes 10 µg Source Native Species Bovine

Human HMGB1 full length protein - ab56525 from Abcam Category Protein Source E. coli Species Human

Human HMGB1 full length protein - ab81876 from Abcam Category Protein Source E. coli Species Human

Human HMGB1 full length protein - ab151644 from Abcam Category Protein Source HEK 293 cells Species Human

Human HMGB1 full length protein - ab78940 from Abcam Category Protein Source Baculovirus infected High-5 cells Species Human

Human HMGB1 full length protein - ab73658 from Abcam Category Protein Source E. coli Species Human

Human HMGB1 peptide - ab18650 from Abcam Category Peptide

Human HMGB1 protein fragment - ab188457 from Abcam Category Protein Source E. coli Species Human

HMG1 / HMGB1 Antibody Blocking Peptide - LS-E4988 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HMG1 / HMGB1 Antibody Blocking Peptide - LS-E13675 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HMG1 / HMGB1 Antibody Blocking Peptide - LS-E21592 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HMGB1/HMG-1 Protein - NBC1-18488 from Novus Biologicals Category Protein Prices $349.00 Sizes 100 µg Source Baculovirus Species Human

Recombinant Human HMGB1/HMG-1 His (C-Term) Protein - NBP2-34960 from Novus Biologicals Category Protein Prices $69.00, $169.00, $2,469.00 Sizes 10 µg, 50 µg, 1 mg Source E. coli Species Human

HMGB1/HMG-1 Blocking Peptide - NB100-2322PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg

Recombinant Human HMGB1/HMG-1 Protein - H00003146-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HMGB1/HMG-1 Partial Recombinant Protein - H00003146-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

HMG1L10-Antibody-N-term-Blocking-peptide - BP12194a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HMGB1-Antibody-Center-Blocking-peptide - BP13425c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HMGB1-Antibody-C-term-Blocking-Peptide - BP17386b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human HMGB1, CF - 1690-HMB-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Met1-Glu215

HMGB1 Protein (OPPA01571) - OPPA01571 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg Source E. Coli

HMGB1 Protein (OPPA01746) - OPPA01746 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source Hi-5 Insect Cells

Human HMGB1 protein (His Tag) - orb139021 from Biorbyt Category Protein Prices $400.00, $646.00 Sizes 20 μg, 50 μg Source E. coli Species Human

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