HMGB1

Gene Symbol	HMGB1
Entrez Gene	3146
Alt Symbol	HMG1, HMG3, SBP-1
Species	Human
Gene Type	protein-coding
Description	high mobility group box 1
Other Description	Amphoterin|HMG-1|Sulfoglucuronyl carbohydrate binding protein|high mobility group protein 1|high mobility group protein B1|high-mobility group (nonhistone chromosomal) protein 1|high-mobility group box 1
Swissprots	Q14321 A5D8W9 P09429 Q6IBE1 Q5T7C3
Accessions	AAB08987 AAF71287 AAK64599 ABM47301 ABS29271 EAX08457 EAX08458 EAX08459 EAX08460 EAX08461 EAX08462 P09429 AA430980 AB208998 BAD92235 AF401215 AK057120 BAG51867 AK122825 BAG53745 AK291494 BAF84183 AK304506 BAH14201 AK310975 AL110194 AX795278 CAE48262 AY377859 AAQ91389 BC003378 AAH03378 BC030981 AAH30981 BC066889 AAH66889 BC067732 AAH67732 BC140013 AAI40014 BC140018 AAI40019 BC141844 AAI41845 BT006940 AAP35586 BT020159 AAV38961 BX647267 CR456863 CAG33144 CR749614 CAH18408 D63874 BAA09924 L13804 L13805 X12597 CAA31110 XM_005266363 XP_005266420 XM_005266365 XP_005266422 XM_005266368 XP_005266425 XM_011535055 XP_011533357 XM_011535056 XP_011533358 XR_941568 NM_002128 NP_002119
Function	DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus. Chromosome.
Top Pathways	Base excision repair

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HMG-1 CRISPR/Cas9 KO Plasmid (h) - sc-400735 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

HMG-1 HDR Plasmid (h) - sc-400735-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HMG-1 Double Nickase Plasmid (h) - sc-400735-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HMG-1 Double Nickase Plasmid (h2) - sc-400735-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HMG-1 CRISPR Activation Plasmid (h) - sc-400735-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

HMG-1 CRISPR Activation Plasmid (h2) - sc-400735-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

HMG-1 Lentiviral Activation Particles (h) - sc-400735-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HMG-1 Lentiviral Activation Particles (h2) - sc-400735-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HMG-1 siRNA (h) - sc-37982 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HMG-1 shRNA Plasmid (h) - sc-37982-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HMG-1 shRNA (h) Lentiviral Particles - sc-37982-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HMGB1/HMG-1 RNAi - H00003146-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU072991 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU106491 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2055 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2055 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

HMGB1 siRNA (Human) - CRH2147 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

HMGB1 - MBS8225123 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human HMGB1(NM_002128.4) - SHH125075 from Creative biogene Category siRNA Species Reactivities Human

Human HMGB1 siRNA - orb262649 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

HMGB1 shRNA Plasmid (Human) - CHH2147 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

HMGB1 miRNA 3'UTR clone - MiUTR1H-04601 from Creative biogene Species Reactivities Human

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