Gene Symbol | Traf5 |
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Entrez Gene | 22033 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | TNF receptor-associated factor 5 |
Other Description | - |
Swissprots | P70191 Q61480 |
Accessions | EDL12971 P70191 AK141097 AK144694 BAE26019 BC012702 AAH12702 BC038645 BE691772 BY290436 D78141 BAA11218 D83528 BAA11942 NM_011633 NP_035763 |
Function | Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR. {ECO:0000269|PubMed:15121867}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, cytosol. |
Top Pathways | Small cell lung cancer, Herpes simplex infection, Viral carcinogenesis, Epstein-Barr virus infection, TNF signaling pathway |
TRAF5 CRISPR/Cas9 KO Plasmid (m) - sc-423496 from Santa Cruz Biotechnology
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TRAF5 HDR Plasmid (m) - sc-423496-HDR from Santa Cruz Biotechnology
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TRAF5 Double Nickase Plasmid (m) - sc-423496-NIC from Santa Cruz Biotechnology
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TRAF5 Double Nickase Plasmid (m2) - sc-423496-NIC-2 from Santa Cruz Biotechnology
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TRAF5 CRISPR Activation Plasmid (m) - sc-423496-ACT from Santa Cruz Biotechnology
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TRAF5 CRISPR Activation Plasmid (m2) - sc-423496-ACT-2 from Santa Cruz Biotechnology
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TRAF5 Lentiviral Activation Particles (m) - sc-423496-LAC from Santa Cruz Biotechnology
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TRAF5 Lentiviral Activation Particles (m2) - sc-423496-LAC-2 from Santa Cruz Biotechnology
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TRAF5 siRNA (m) - sc-36716 from Santa Cruz Biotechnology
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TRAF5 shRNA Plasmid (m) - sc-36716-SH from Santa Cruz Biotechnology
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TRAF5 shRNA (m) Lentiviral Particles - sc-36716-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN43374 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND43374 from Sigma-Aldrich
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TRAF5 siRNA (Mouse) - CRM4235 from Cohesion Biosciences
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TRAF5 - MBS8222625 from MyBioSource
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shRNA set against Mouse TRAF5 (NM_011633.1) - SHH433768 from Creative biogene
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shRNA set against Mouse Traf5(NM_011633.1) - SHL091306 from Creative biogene
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Mouse TRAF5 siRNA - orb283711 from Biorbyt
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TRAF5 shRNA Plasmid (Mouse) - CHM4235 from Cohesion Biosciences
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TRAF5 miRNA 3'UTR clone - MiUTR1M-12080 from Creative biogene
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