DAG1

Gene Symbol DAG1
Entrez Gene 1605
Alt Symbol 156DAG, A3a, AGRNR, DAG, MDDGC7, MDDGC9
Species Human
Gene Type protein-coding
Description dystroglycan 1 (dystrophin-associated glycoprotein 1)
Other Description dystroglycan
Swissprots Q14118 A8K6M7 Q969J9
Accessions EAW64989 EAW64990 Q14118 AK291692 BAF84381 AK297802 BAG60140 AU140753 AW204012 BC012740 AAH12740 BC014616 AAH14616 BF476692 BM990874 BP200440 BX384229 BX402174 CN282379 CX871468 DA223570 DA338757 DA451012 DA698126 DA843040 DA851197 DB065493 DB087722 DB089586 DB214431 DB214875 DQ893491 ABM84417 DQ896435 ABM87434 L19711 AAA81779 NM_001165928 NP_001159400 NM_001177634 NP_001171105 NM_001177635 NP_001171106 NM_001177636 NP_001171107 NM_001177637 NP_001171108 NM_001177638 NP_001171109 NM_001177639 NP_001171110 NM_001177640 NP_001171111 NM_001177641 NP_001171112 NM_001177642 NP_001171113 NM_001177643 NP_001171114 NM_001177644 NP_001171115 NM_004393 NP_004384
Function Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
Subcellular Location Alpha-dystroglycan: Secreted, extracellular space.
Tissue Specificity Expressed in a variety of fetal and adult tissues. In epidermal tissue, located to the basement membrane. Also expressed in keratinocytes and fibroblasts. {ECO:0000269|PubMed:15175026, ECO:0000269|PubMed:8268918}.
Top Pathways ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

α-dystroglycan (D-3) - sc-271589 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α-dystroglycan (D-3): sc-271589. Western blot analysis of α-dystroglycan expression in DU 145 whole cell lysate.

α-dystroglycan (2237E2D1) - sc-65628 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α-dystroglycan (2237E2D1): sc-65628. Western blot analysis of α-dystroglycan expression in cow brain tissue extract.

α-dystroglycan (2238E2D2) - sc-65629 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

α-dystroglycan (C-15) - sc-46052 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

α-dystroglycan (H-300) - sc-28534 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
α-dystroglycan (H-300): sc-28534. Western blot analysis of α-dystroglycan expression in mouse brain tissue extract.

α-dystroglycan (IIH6) - sc-53987 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α-dystroglycan (IIH6): sc-53987. Western blot analysis of α-dystroglycan expression in human brain (A) and human skeletal muscle (B) tissue extracts.

α-dystroglycan (F-18) - sc-16162 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

α-dystroglycan (IIH6C4) - sc-73586 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α-dystroglycan (IIH6C4): sc-73586. Western blot analysis of α-dystroglycan expression in mouse brain (A) and rat brain (B) tissue extracts.

α-dystroglycan (E-21) - sc-22320 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

α-dystroglycan (N-15) - sc-46054 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
α-dystroglycan (N-15): sc-46054. Western blot analysis of human recombinant α-dystroglycan fusion protein.

α-dystroglycan (N-18) - sc-46055 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
α-dystroglycan (N-18): sc-46055. Western blot analysis of α-dystroglycan expression in mouse skeletal muscle (A) and rat skeletal muscle (B) tissue extracts.

α-dystroglycan (VIA4 1 ) - sc-53986 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α-dystroglycan (VIA4<sub>1</sub>): sc-53986. Western blot analysis of α-dystroglycan expression in bovine brain tissue extract.

α-dystroglycan (W-15) - sc-33436 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
αdystroglycan (W-15): sc-33436. Western blot analysis of αdystroglycan expression in NIH/3T3 (A), JAR (B) and MCF7 (C) whole cell lysates.

β-dystroglycan (4F7) - sc-33702 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
β-dystroglycan (4F7): sc-33702. Immunofluorescence staining of methanol-fixed L6 cells showing membrane localization.

β-dystroglycan (7D11) - sc-33701 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
β-dystroglycan (7D11): sc-33701. Immunofluorescence staining of methanol-fixed L6 cells showing membrane localization.

β-dystroglycan (A-9) - sc-165999 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
β-dystroglycan (A-9): sc-165999. Western blot analysis of β-dystroglycan expression in MCF7 (A) and C6 (B) whole cell lysates and rat skeletal muscle tissue extract (C).

β-dystroglycan (B-4) - sc-165997 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
β-dystroglycan (B-4): sc-165997. Western blot analysis of β-dystroglycan expression in MCF7 (A) and C6 (B) whole cell lysates and rat skeletal muscle tissue extract (C).

β-dystroglycan (B-6) - sc-165998 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
β-dystroglycan (B-6): sc-165998. Western blot analysis of β-dystroglycan expression in MCF7 whole cell lysate.

β-dystroglycan (C-20) - sc-16165 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
β-dystroglycan (C-20): sc-16165. Western blot analysis of β-dystroglycan expression in rat skeletal muscle tissue extract (A) and C6 (B), SK-BR-3 (C) and L6 (D) whole cell lysates.

β-dystroglycan (F-15) - sc-26539 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
β-dystroglycan (F-15): sc-26539. Immunofluorescence staining of methanol-fixed MCF7 cells showing membrane localization.

β-dystroglycan (H-242) - sc-28535 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
β-dystroglycan (H-242): sc-28535. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

β-dystroglycan (K-13) - sc-30403 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
β-dystroglycan (K-13): sc-30403. Western blot analysis of β-dystroglycan expression in MCF7 (A), C6 (B),SK-BR-3 (C) and L6 (D) whole cell lysates.

β-dystroglycan (L-20) - sc-30405 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
β-dystroglycan (L-20): sc-30405. Western blot analysis of β-dystroglycan expression in C6 (A) and L6 (B) whole cell lysates.

β-dystroglycan (N-14) - sc-26538 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
β-dystroglycan (N-14): sc-26538. Immunofluorescence staining of methanol-fixed MCF7 cells showing membrane localization.

β-dystroglycan (P-14) - sc-30404 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
β-dystroglycan (P-14): sc-30404. Western blot analysis of β-dystroglycan expression in C6 (A), SK-BR-3 (B) and L6 (C) whole cell lysates.
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