DAG1

Gene Symbol	DAG1
Entrez Gene	1605
Alt Symbol	156DAG, A3a, AGRNR, DAG, MDDGC7, MDDGC9
Species	Human
Gene Type	protein-coding
Description	dystroglycan 1 (dystrophin-associated glycoprotein 1)
Other Description	dystroglycan
Swissprots	Q14118 A8K6M7 Q969J9
Accessions	EAW64989 EAW64990 Q14118 AK291692 BAF84381 AK297802 BAG60140 AU140753 AW204012 BC012740 AAH12740 BC014616 AAH14616 BF476692 BM990874 BP200440 BX384229 BX402174 CN282379 CX871468 DA223570 DA338757 DA451012 DA698126 DA843040 DA851197 DB065493 DB087722 DB089586 DB214431 DB214875 DQ893491 ABM84417 DQ896435 ABM87434 L19711 AAA81779 NM_001165928 NP_001159400 NM_001177634 NP_001171105 NM_001177635 NP_001171106 NM_001177636 NP_001171107 NM_001177637 NP_001171108 NM_001177638 NP_001171109 NM_001177639 NP_001171110 NM_001177640 NP_001171111 NM_001177641 NP_001171112 NM_001177642 NP_001171113 NM_001177643 NP_001171114 NM_001177644 NP_001171115 NM_004393 NP_004384
Function	Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
Subcellular Location	Alpha-dystroglycan: Secreted, extracellular space.
Tissue Specificity	Expressed in a variety of fetal and adult tissues. In epidermal tissue, located to the basement membrane. Also expressed in keratinocytes and fibroblasts. {ECO:0000269|PubMed:15175026, ECO:0000269|PubMed:8268918}.
Top Pathways	ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human beta Dystroglycan peptide - ab43750 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human DAG1 protein fragment - ab112278 from Abcam Category Protein Source Wheat germ Species Human

Human DAG1 protein fragment - ab175460 from Abcam Category Protein Source E. coli Species Human

DAG1 / Dystroglycan Antibody Blocking Peptide - LS-E2970 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DAG1 / Dystroglycan Antibody Blocking Peptide - LS-E27390 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DAG1 / Dystroglycan Antibody Blocking Peptide - LS-E16935 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DAG1 / Dystroglycan Antibody Blocking Peptide - LS-E16934 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Alpha Dystroglycan Protein - H00001605-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DAG1-Antibody-C-term-Blocking-peptide - BP14101b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DAG1 blocking peptide - GTX88089-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Recombinant Human Dystroglycan, CF - 6868-DG-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Met1-Val749, with a C-terminal 6-His tag

Human DAG1 protein - orb191246 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli Species Human

Human Dystroglycan (His Tag) protein - orb232331 from Biorbyt Category Protein Prices $400.00, $816.00 Sizes 50 μg, 200 μg Species Human

DAG1 Immunizing peptide - orb59826 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

DAG1 Blocking Peptide - 33R-1265 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Dag1 Blocking Peptide - 33R-7277 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DAG1 Peptide - AC21-2214-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Dystroglycan - H00001605-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Dystroglycan - H00001605-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DAG1 Peptide - 42-607P from ProSci Category Peptide Species Human, Mouse, Rat

DAG1 fusion protein - ag1456 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human DAG1 - DAG1-26240TH from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human DAG1 - DAG1-200H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human DAG1 Protein, His-tagged - DAG1-549H from Creative Biomart Category Protein Source NSO Cells Species Human

Recombinant Dystrophin Associated Glycoprotein 1 (DAG1) - RPC448Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

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