RHOA

Gene Symbol	RHOA
Entrez Gene	387
Alt Symbol	ARH12, ARHA, RHO12, RHOH12
Species	Human
Gene Type	protein-coding
Description	ras homolog family member A
Other Description	Aplysia ras-related homolog 12|h12|oncogene RHO H12|ras homolog gene family, member A|rho cDNA clone 12|small GTP binding protein RhoA|transforming protein RhoA
Swissprots	Q9UDJ0 Q53HM4 Q5U024 Q9UEJ4 P06749 P61586
Accessions	AAA67539 CAL40338 EAW64978 EAW64979 EAW64980 P61586 AF498970 AAM21117 AK130066 AK130808 AK222556 BAD96276 AK296654 BAG59251 AK307220 BC000946 AAH00946 BC001360 AAH01360 BC005976 AAH05976 BT019870 AAV38673 BX647063 CAE46190 EU831594 ACE87194 EU831679 ACE86513 L09159 AAA50612 L25080 AAC33178 LN607834 CEF49521 X05026 CAA28690 XM_011533695 XP_011531997 NM_001664 NP_001655
Function	Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA- DIAPH1 signaling pathway plays an important role in ERBB2- dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membr
Subcellular Location	Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cytoplasm, cell cortex {ECO:0000269|PubMed:9635436}. Midbody. Cell projection, lamellipodium {ECO:0000250}. Note=Localized to cell-cell contacts in calcium-treated keratinocytes (By similarity). Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. Localizes to the equatorial cell cortex (at the site of the presumptive furrow) in early anaphase in a activated form and in a myosin- and actin-independent manner. {ECO:0000250}.
Top Pathways	cGMP-PKG signaling pathway, Oxytocin signaling pathway, cAMP signaling pathway, Rap1 signaling pathway, MicroRNAs in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active Rho Detection Kit - 8820 from Cell Signaling Technology Category Cellular Assay Prices $719.00 Sizes 1 kit (30 rxns)

Human RHOA ELISA Kit (Sandwich ELISA) - LS-F9125 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.057 ng/ml Range 0.156-10 ng/ml

Ras Homolog Gene Family, Member A (RHOA), Human, ELISA Kit - SEE320Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.057ng/mL. Range 0.156-10ng/mL

Ras Homolog Gene Family, Memmber A, RHOA, Human, ELISA Kit - E-EL-H0922 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 46.875 Range 78.125-5000pg/mL

Transforming protein RhoA, RHOA, Human, ELISA Kit - E9513h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 0.156-10 ng/mL

Ras Homolog Gene Family, Memmber A, RHOA, Rabbit, ELISA Kit - E-EL-RB0756 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Ras Homolog Gene Family, Memmber A, RHOA, Chicken, ELISA Kit - E-EL-Ch0234 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Ras Homolog Gene Family, Memmber A, RHOA, Porcine, ELISA Kit - E-EL-P0473 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Ras Homolog Gene Family, Memmber A, RHOA, Sheep, ELISA Kit - E-EL-S0221 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Ras Homolog Gene Family, Memmber A, RHOA, Guinea Pig, ELISA Kit - E-EL-GP0091 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Ras Homolog Gene Family, Memmber A, RHOA, Monkey, ELISA Kit - E-EL-MK2036 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Rhoa Protein, ELISA Kit - MBS042156 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rhoa Protein, ELISA Kit - MBS086001 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rhoa Protein, ELISA Kit - MBS069374 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RhoA Protein, ELISA Kit - MBS746774 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human RHOA(Ras Homolog Gene Family, Memmber A) ELISA Kit - E-EL-H0922 from Elabscience Category ELISA Kit Sensitivity 46.88 pg/mL Range 78.13—5000 pg/mL

ras homolog gene family, member A, ELISA Kit - MBS9335451 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5.0 pg/ml Range 31.2 pg/ml - 1000 pg/ml

Ras Homolog Gene Family, Member A (RHOA), ELISA Kit - MBS2023112 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of RHOA is typically less than 0.057ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

Rhoa Protein, ELISA Kit - MBS075538 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rhoa Protein, ELISA Kit - MBS079698 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rhoa Protein, ELISA Kit - MBS024961 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Ras Homolog Gene Family, Member A (RHOA) - SEE320Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.057ng/mL.. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Rho Activation Assay Kit - 17-294 from EMD Millipore Category Assay Kit

ELISA Kit for Ras Homolog Gene Family, Member A (RHOA) - SEE320Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.057ng/mL.. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Bovine RHOA ELISA Kit (Custom ELISA) - LS-F20456 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

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