Gene Symbol |
CHRNB3
|
Entrez Gene |
1142
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cholinergic receptor, nicotinic, beta 3 (neuronal)
|
Other Description |
acetylcholine receptor, neuronal nicotinic, beta-3 subunit|acetylcholine receptor, nicotinic, beta 3 (neuronal)|cholinergic receptor, nicotinic, beta polypeptide 3|neuronal acetylcholine receptor subunit beta-3
|
Swissprots |
Q05901 Q15827
|
Accessions |
AAD33063 EAW63208 Q05901 BC069681 AAH69681 BC069703 AAH69703 BC069788 AAH69788 HQ447438 ADQ31924 U62438 AAB40116 X67513 CAA47851 Y08417 CAA69694 XM_011544390 XP_011542692 NM_000749 NP_000740
|
Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|
Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
Neuroactive ligand-receptor interaction
|