CHRNB3
| Gene Symbol | CHRNB3 |
|---|---|
| Entrez Gene | 1142 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | cholinergic receptor, nicotinic, beta 3 (neuronal) |
| Other Description | acetylcholine receptor, neuronal nicotinic, beta-3 subunit|acetylcholine receptor, nicotinic, beta 3 (neuronal)|cholinergic receptor, nicotinic, beta polypeptide 3|neuronal acetylcholine receptor subunit beta-3 |
| Swissprots | Q05901 Q15827 |
| Accessions | AAD33063 EAW63208 Q05901 BC069681 AAH69681 BC069703 AAH69703 BC069788 AAH69788 HQ447438 ADQ31924 U62438 AAB40116 X67513 CAA47851 Y08417 CAA69694 XM_011544390 XP_011542692 NM_000749 NP_000740 |
| Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
| Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Top Pathways | Neuroactive ligand-receptor interaction |
AChRβ3 siRNA (h) - sc-42538 from Santa Cruz Biotechnology
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AChRβ3 shRNA Plasmid (h) - sc-42538-SH from Santa Cruz Biotechnology
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AChRβ3 shRNA (h) Lentiviral Particles - sc-42538-V from Santa Cruz Biotechnology
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CHRNB3 RNAi - H00001142-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN6100 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6100 from Sigma-Aldrich
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CHRNB3 siRNA (Human) - CRH0819 from Cohesion Biosciences
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CHRNB3 - MBS8226821 from MyBioSource
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shRNA set against Human CHRNB3 (NM_000749.3) - SHH263645 from Creative biogene
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shRNA set against Human CHRNB3(NM_000749.3) - SHG177499 from Creative biogene
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CHRNB3 shRNA Plasmid (Human) - CHH0819 from Cohesion Biosciences
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CHRNB3 miRNA 3'UTR clone - MiUTR1H-02149 from Creative biogene
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