USP1

Gene Symbol USP1
Entrez Gene 7398
Alt Symbol UBP
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 1
Other Description deubiquitinating enzyme 1|hUBP|ubiquitin carboxyl terminal hydrolase 1|ubiquitin carboxyl-terminal hydrolase 1|ubiquitin specific processing protease 1|ubiquitin specific protease 1|ubiquitin thioesterase 1|ubiquitin thiolesterase 1|ubiquitin-specific-processing protease 1
Swissprots A0PJ95 Q05BX7 Q9UFR0 Q59H66 D3DQ57 O94782 Q9UNJ3
Accessions EAX06585 EAX06586 O94782 AB014458 BAA34703 AB208893 BAD92130 AF117386 AAD11441 AK096788 AK312423 BAG35333 AL117503 CAB55967 AL117575 CAB55999 AL599240 AM392756 CAL37634 BC011881 BC018745 AAH18745 BC023216 BC032364 AAH32364 BC040140 BC050525 AAH50525 BI463072 BQ018843 BQ186837 NM_001017415 NP_001017415 NM_001017416 NP_001017416 NM_003368 NP_003359
Function Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. {ECO:0000269|PubMed:15694335, ECO:0000269|PubMed:16531995, ECO:0000269|PubMed:18082604}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15694335}.
Top Pathways Fanconi anemia pathway

USP1 293T Cell Transient Overexpression Lysate(Denatured) - H00007398-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

USP1 overexpression lysate - LY418724 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

USP1 overexpression lysate - LY422784 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

USP1 overexpression lysate - LY422785 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

USP1 overexpression lysate - LY425405 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

USP1 293 Cell Lysate - 409794 from ABBIOTEC

Category Cell Lysate
Prices $672.00
Sizes 100 µg

USP1 Overexpression Lysate (Native) - NBL1-17642 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: USP1 Overexpression Lysate (Adult Normal) [NBL1-17642] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for USP1.

USP1 Overexpression Lysate (Native) - NBP2-08684 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg

USP1 Overexpression Lysate (Native) - NBP2-09159 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg

USP1 Over-expression Lysate Product - GWB-D1DBDB from Genway Biotech

Category Cell Lysate
Prices $756.00
Sizes 100 µg
Species Human

USP1 Overexpression Lysate (Denatured) - H00007398-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human USP1 Knockdown Stable Cell Line - CSC-DC017146 from Creative biogene

Category Cell Line
Species Human
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